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Does Zyclara work for genital warts?

Medically reviewed by Leigh Ann Anderson, PharmD. Last updated on Sep 11, 2024.

Official Answer by Drugs.com

The 3.75% strength of Zyclara topical cream is approved by the FDA to treat external gential and anal area (perianal) warts in people 12 years of age and older, but does not work for everyone. Zyclara is not a cure for genital warts and may not completely clear your warts.

You may still spread this condition to others through vaginal, anal, or oral sex. You also may develop new lesions during treatment.

How is Zyclara applied for genital warts?

For the treatment of genital warts, topical Zyclara (imiquimod) cream 3.75% is applied once daily for up to 8 weeks. Topical medicine should only be used on the skin. Follow your doctor’s instructions exactly. For best results, keep using the medicine for the entire length of time prescribed by your doctor.

How well did Zyclara work in studies for gential warts?

In two double-blind, randomized, placebo-controlled clinical studies, 601 subjects with external gential warts were treated with 3.75% Zyclara cream or a matching placebo (inactive) vehicle cream.

Up to one packet of study cream was applied once daily. The cream was applied to warts areas before bedtime and left on for about 8 hours for up to 8 weeks or until complete clearance of all warts. Complete clearance was defined as clearance of all warts in all areas within 16 weeks from the beginning of treatment.

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Who makes Zyclara and where is it manufactured?

Zyclara Cream is manufactured by Bausch Health Companies Inc. located in Laval, Quebec, Canada. The US headquarters for Bausch Health US is in Bridgewater, NJ. You can contact Bausch Health customer support at 1-800-321-4576 or online. Continue reading

Why do I have bumps or warts in the genital area?

Bumps or warts in the genital area are often a sign of genital warts, a sexually transmitted infection caused by certain strains of the human papillomavirus (HPV). Genital warts can appear as small, flesh-colored bumps or cauliflower-like growths, and they can develop around the genitals, anus, or surrounding skin. Continue reading

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