What is the difference between Polysporin and Neosporin?

Neosporin contains neomycin which is not present in polysporin.
Polysporin is the brand name for a product containing bacitracin zinc and polymyxin B sulfate.
Neosporin is the brand name for a product containing bacitracin zinc, polymyxin B sulfate and neomycin sulfate.

They are both antibiotics used to treat infections and are available in several topical dosage forms ie eye drops, cream etc.

See: https://www.drugs.com/pro/neosporin.html
https://www.drugs.com/pro/polysporin.html

See also:

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