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Medrol Dosepak - How long does a dose pack stay in your system?

Medically reviewed by Drugs.com Last updated on Sep 13, 2018.

Official Answer

by Drugs.com

After taking a single dose of Medrol Dosepak it should be out of your system after 8 days (5.5 x 36 hours = 198 hours or just over 8 days).

Medrol Dosepak (methylprednisolone) has a medium half life range of 18 to 36 hours - meaning it takes the body 18 to 36 hours to clear 50% of the drug from your plasma.
For a drug to be totally eliminated from your system it takes around 5.5 times the half life.

Other factors to consider:
1. How much and how often you have taken the drug.
2. Your metabolic rate – a slower metabolism will increase the time a drug remains in your system.
3. Your age and health – older age and poor health will generally increase the time the drug stays in your system.
4. Body mass – generally the bigger you are the longer a drug will remain in your system.

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