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Does Humira make you feel tired?

Medically reviewed by Sally Chao, MD. Last updated on July 1, 2022.

Official answer


Generally, Humira should not make you feel tired. Tiredness has not been reported as a side effect of this medication. However, being tired might be a symptom of other possible side effects such as an infection or liver problems. The most common side effects of Humira are:

  • Infections
  • Reactions at the site of the injection
  • Headache
  • Rash

You should report any symptom(s) that bother you or don't go away to the doctor who prescribed the medicine.

Humira is the brand name for the medication adalimumab. It is approved for the treatment of several diseases including:

  • Ankylosing Spondylitis
  • Crohn's disease
  • Juvenile idiopathic arthritis
  • Plaque Psoriasis
  • Psoriatic arthritis
  • Rheumatoid arthritis
  • Ulcerative colitis
  • Uveitis
  1. U.S. National Library of Medicine DailyMed. Humira. February 2021. Available at: [Accessed June 10, 2022].
  2. National Institute of Allergy and Infectious Disease. Overview of the Immune System. December 30, 2013. Available at: [Accessed June 8, 2022].

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