Skip to main content

What is the difference between Symjepi and EpiPen?

Medically reviewed by Leigh Ann Anderson, PharmD. Last updated on March 21, 2023.

Official answer


EpiPen and Symjepi are both intramuscular or subcutaneous injections use to treat allergic emergencies (anaphylaxis), for example to bees stings or peanuts. Unlike EpiPen, Symjepi does not come as an "autoinjector" but comes only as a prefilled syringe. Symjepi has a smaller size and may be more user-friendly than other products.

Related: EpiPen and Symjepi Pricing Guide

Like EpiPen, Symjepi (epinephrine) is a single-dose, prefilled syringe of 0.3 mg or 0.15 mg epinephrine used for emergency treatment of Type 1 allergic reactions such as insect stings, food allergies (like nuts or shellfish), or medications, among other severe allergic reactions.

Symjepi and EpiPen injectors are both designed for injection through clothing, but the users of Symjepi should be in a seated position prior to injection in the outer thigh, while the EpiPen can be used while standing. Seek medical attention immediately after using Symjepi or EpiPen.

Symjepi, from Adamis, was FDA-approved in June 2017 and is sold in a 2-pack like EpiPen.

Other brands of epinephrine include Auvi-Q from Kaleo and Adrenaclick from Impax. Generic alternatives are also available on the U.S. market for emergency epinephrine delivery.

See also: Comparing EpiPen vs Symjepi

This is not all the information you need to know about Symjepi or EpiPen for safe and effective use and does not take the place of talking to your doctor about your treatment. Review the full product information here, and discuss this information and any questions you have with your doctor or other health care provider.


Related medical questions

Drug information

Related support groups