Skip to main content

How is Cotempla XR-ODT different to other brands of methylphenidate?

Medically reviewed by Judith Stewart, BPharm. Last updated on Feb 14, 2024.

Official answer

by Drugs.com

Cotempla XR-ODT is the first once-daily, extended-release, orally disintegrating tablet (ODT) formulation of the stimulant methylphenidate.

This ODT formulation is designed to dissolve on the tongue without the need to swallow with water.

Cotempla XR-ODT (methylphenidate) was approved in June 2017 for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in pediatric patients 6 to 17 years of age. It is not approved for use in adults.

Cotempla XR-ODT tablets are administered once daily in the morning.

Cotempla XR-ODT contains methylphenidate which is a Schedule II Controlled Substance, which means it has a high potential for abuse and dependence.

  • Cotempla XR-ODT must be stored in a safe place, preferably locked, to prevent misuse.
  • Cotempla XR-ODT must not be given to anyone else. Selling or giving away Cotempla XR-ODT may harm others and is against the law.
  • Any unused or expired Cotempla XR-ODT should be disposed of through a medicine take-back program if available.

There are many brands of methylphenidate on the U.S market with multiple dosage forms, including:

  • tablets (Ritalin)
  • extended-release tablets (Concerta, Methylin ER, Relexxii)
  • extended-release capsules (Adhansia XR, Aptensio XR, Jornay PM, Metadate CD, Ritalin LA)
  • extended-release chewable tablets (Quillichew ER)
  • extended-release orally disintegrating tablets (Cotempla XR-ODT)
  • transdermal system (Daytrana)
  • oral solution (Methylin)
  • powder for extended-release oral suspension (Quillivant XR)

For more information, see What are the brands of methylphenidate?

Related questions

Read next

Adderall vs Vyvanse - What's the difference between them?

The main difference between Adderall and Vyvanse is that Adderall is a mixture of four different kinds of amphetamine salts (one of which is dextroamphetamine) while Vyvanse only contains one type of amphetamine salt, called lisdexamfetamine. Lisdexamfetamine gets converted into dexamphetamine once it is in the body. One advantage of Vyvanse is that it may be less likely to be abused; although it is slightly more expensive than Adderall, although both have generic forms available. Because both drugs contain amphetamines, they work in a similar way. Studies have shown that Vyvanse is just as effective as Adderall, and side effects, including the risk of dependence, are similar. Continue reading

How soon for Vyvanse to start working and how long does it last?

For ADHD: In adults, Vyvanse was shown in clinical studies to improve attention at 2 hours and up to 14 hours after taking a dose. In children aged 6-12, Vyvanse was shown to start working within 1.5 hours and up to 13 hours after the morning dose. For binge eating disorder, it can take up to 12 weeks for patients to show a significant reduction in their number of binge days per week. Continue reading

What are 12 key Strattera side effects to watch out for?

Common side effects of Strattera include headache, poor appetite, and nausea. It can also cause dry mouth, drowsiness, trouble sleeping, and an increase in blood pressure and heart rate. Strattera can raise the risk of suicidal thoughts in children and adolescents. Rare cases of liver damage have also been reported. Continue reading

Related medical questions

Drug information

Related support groups