Does Caplyta cause weight gain?
Caplyta (lumateperone) is not typically associated with weight gain, a common concern with some antipsychotic medications. It is an atypical antipsychotic used to treat schizophrenia and bipolar depression in adults.
Clinical Trial Results on Weight Gain
A review of multiple clinical trials found that weight gain in patients treated with Caplyta was comparable to those who received a placebo.
A separate long-term study observed patients who switched from standard antipsychotic treatments to Caplyta for one year. Results showed:
- A significant reduction in mean body weight (-2.1 kg, P <0.001).
- Decreases in body mass index (BMI) and waist circumference over time.
These findings suggest that Caplyta may be a suitable option for patients concerned about weight gain with antipsychotic treatment. Always consult your healthcare provider to discuss potential side effects and the best treatment approach for your condition.
References
- Caplyta Prescribing Information. https://www.intracellulartherapies.com/docs/caplyta_pi.pdf
- Satlin A, Durgam S, Vanover KE, et al. M205. Long-term safety of lumateperone (ITI-007): Metabolic effects in a 1-year study. Schizophr Bull. 2020;46(Suppl 1):S214. doi:10.1093/schbul/sbaa030.517.
Read next
What is the mechanism of action for Caplyta?
Caplyta (lumateperone) is thought to work by changing the activity of certain chemicals called neurotransmitters in the brain. These neurotransmitters include dopamine, glutamate, and serotonin. Continue reading
Caplyta savings card: Do I qualify and how much can I save?
To be eligible for the Caplyta Savings Card, you must be 18 years of age or older, have a prescription for Caplyta, and have private commercial insurance. It cannot be used with federal or state health programs. If you qualify, you may pay as little as $0 for the first two fills of a 30-day supply of Caplyta, up to the maximum lifetime benefit which is based on the current list price of a 30-day supply. After that, you pay $15 for fills up to a 90-day supply (maximum benefit $600). Continue reading
How long does it take Caplyta to work?
Patient with schizophrenia started to show improved Positive and Negative Syndrome Scale (PANSS) total scores after one week of treatment with Caplyta (lumateperone), according to the results of a phase III trial. PANSS is a scale used to measure the severity of schizophrenia symptoms. Symptoms continue to improve the longer you take the drug. Continue reading
See also:
Aimovig
Learn about Aimovig (erenumab-aooe) a once-monthly, injectable medication that can be ...
Botox
Botox is used for cosmetic purposes and to treat overactive bladder symptoms, urinary incontinence ...
Vraylar
Vraylar is a once a day antipsychotic medication used to treat mental health or mood disorders ...
Nurtec ODT
Nurtec ODT (rimegepant) is used to treat acute migraines and prevent episodic migraines, by ...
Emgality
Emgality (galcanezumab-gnlm) is a CGRP antagonist for the preventive treatment of migraine and for ...
Inderal
Inderal (propranolol) is used to treat angina, high blood pressure and heart rhythm disorders ...
Ajovy
Ajovy (fremanezumab-vfrm) is a preventive migraine treatment. Includes Ajovy side effects ...
Vyepti
Vyepti (eptinezumab-jjmr) is used for the preventive treatment of migraine. Includes Vyepti ...
Botox Cosmetic
Botox Cosmetic is a prescription treatment for fine lines and wrinkles. It temporarily improves the ...
Fremanezumab
Fremanezumab is used for chronic migraine, headache, migraine, migraine prevention
Related medical questions
- Is obesity a major risk factor for Covid-19?
- What is the natural Mounjaro recipe for weight loss?
- Mounjaro vs Ozempic: Which is right for you?
- Zepbound Vs Mounjaro: Complete Comparison Guide for Weight Loss and Diabetes Treatment
- Ozempic Side Effects to Watch For
- Why am I not losing weight on Mounjaro?
- How do Ozempic, Mounjaro, Wegovy, Zepbound compare for weight loss?
- How long does it take for Ozempic to work?
- Wegovy vs Ozempic: Which is Right for You?
- How long to see weight loss results with Wegovy?
- Tirzepatide vs semaglutide: How do they compare?
- Does levothyroxine cause weight gain or loss?
- Does Wellbutrin XL/SR cause weight gain or loss?
- Do Ozempic, Wegovy, Mounjaro & Zepbound cause hair loss?
- How does Ozempic work for weight loss?
- Why does Lexapro cause weight gain?
- What happens when you stop taking Ozempic?
- How much is Zepbound with or without insurance?
- Does Lyrica (pregabalin) cause weight gain?
- Does Ozempic need to be refrigerated?
- Saxenda vs Ozempic: For Weight Loss?
- Does gabapentin cause weight gain?
- Does Zoloft (sertraline) cause weight gain?
- Will my insurance cover the cost of Ozempic?
- How does Mounjaro Work for Weight Loss?
- How long does it take for Zepbound to work?
- Can you get tirzepatide from a compounding pharmacy?
- Does Prozac cause weight gain or loss?
- Does topiramate cause weight loss?
- Is Mounjaro covered by insurance or Medicare?
Drug information
- Caplyta Information for Consumers
- Caplyta prescribing info & package insert (for Health Professionals)
- Side Effects of Caplyta (detailed)
- Caplyta user reviews (188)
Related support groups
- Caplyta (6 questions, 10 members)
- Weight Loss (Obesity/Overweight) (850 questions, 1,510 members)
- Schizophrenia (103 questions, 325 members)