Does amlodipine cause weight gain?
Weight gain has been reported by some people taking amlodipine but this is not a common side effect and some people have also reported weight loss. Weight gain with amlodipine may also be a symptom of edema, which is when you retain fluid, which may be particularly noticeable around your ankles or lower legs. The risk of edema with amlodipine is greater in women compared with men and in those people taking a higher dosage of amlodipine, and edema is usually noticed as weight gain.
Weight gain is more likely with some other blood pressure medications, such as beta-blockers (examples include atenolol, propranolol, and metoprolol).
References
- Amlodipine [Package insert]. Updated 03/2022. EXELAN PHARMACEUTICALS, INC. https://www.drugs.com/pro/amlodipine.html#s-34084-4
Read next
What is the best time of day to take blood pressure medication?
Research has suggested that taking your blood pressure medication at night instead of in the morning can provide better blood pressure control at night without compromising daytime blood pressure control and reduce your overall risk of dying because of cardiovascular disease by 45%. Continue reading
How do I reduce swelling from amlodipine?
Swelling from amlodipine is a common, but often troublesome side effect of amlodipine with 5% to 9% of people stopping amlodipine because of it. If you develop swelling with amlodipine, tell your doctor right away because they may be able to change your blood pressure medications slightly to help reduce the swelling. Swelling caused by amlodipine does not usually respond to treatment with diuretics (such as furosemide) because it is caused by changes in capillary pressure that result in leakage into the spaces between capillaries (called the interstitial area) rather than water retention. Continue reading
How long does it take for amlodipine to work?
Amlodipine decreases blood pressure over 4 to 8 hours after a single dose. Because the decrease in blood pressure is gradual, a patient's heart rate is not affected because their physiological reflexes (such as an increase in heart rate) are not activated.
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Drug information
- Amlodipine Information for Consumers
- Amlodipine prescribing info & package insert (for Health Professionals)
- Side Effects of Amlodipine (detailed)
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