What is the advantage of ZTlido over Lidoderm?

ZTlido and Lidoderm are both transdermal patches, however ZTlido has been shown to have superior adhesion compared to Lidoderm.

Problems with adhesion are the most widely reported quality defects of transdermal patches.

ZTlido (lidocaine topical system 1.8%) was designed to maintain optimum skin contact throughout the 12-hour administration period to maintain efficient drug delivery. In clinical studies looking at adhesion scores at the end of a 12-hour administration period, 91% (49/54) of the subjects presented with a score of 0 (≥ 90% adhered; essentially no lift off the skin) and 5 subjects had a score of 1 (≥ 75% to < 90% adhered; some edges only lifting off the skin).
In another comparative adhesion study in 44 subjects, ZTlido demonstrated statistically significant superior adhesion (p <0.0001) to Lidoderm (lidocaine topical) at 3 hours that improved over the 12-hour administration period.

Ref: https://www.drugs.com/newdrugs/sorrento-therapeutics-subsidiary-scilex-receives-fda-approval-non-opioid-ztlido-lidocaine-topical-1-4703.html

Read next

See also:

Related medical questions

• What is ZTlido used to treat?
• Lyrica vs Gabapentin: What's the difference?
• Does Lyrica (pregabalin) make you sleepy?
• Is gabapentin addictive?
• Should gabapentin be taken with food?
• Does Qutenza contain red chili peppers?

Drug information

• Lidoderm (89 reviews)

Related support groups

• Lidoderm (22 questions, 39 members)
• ZTlido (3 questions, 3 members)
• Persisting Pain, Shingles (39 questions, 112 members)
• Postherpetic Neuralgia (29 questions, 150 members)

Medical Disclaimer