Macrolides
What are Macrolides?
Macrolides are a class of antibiotics derived from Saccharopolyspora erythraea (originally called Streptomyces erythreus), a type of soil-borne bacteria.
Macrolides inhibit protein synthesis in bacteria by reversibly binding to the P site of the 50S unit of the ribosome. Macrolides mainly affect gram-positive cocci and intracellular pathogens such as mycoplasma, chlamydia, and legionella. Erythromycin was the first macrolide discovered; other macrolides include azithromycin, clarithromycin, and roxithromycin.
Their action is primarily bacteriostatic but may be bactericidal at high concentrations, or depending on the type of microorganism.
List of Macrolides
Drug Name | Avg. Rating | Reviews |
---|---|---|
azithromycin systemic (Pro) Brand names: Zithromax, Azithromycin Dose Pack |
1,308 reviews | |
clarithromycin systemic (Pro) Brand name: Biaxin XL |
853 reviews | |
erythromycin systemic (Pro) Brand names: EryPed, Erythrocin, Ery-Tab, Eryc, Erythrocin Lactobionate, PCE Dispertab, E.E.S. Granules |
67 reviews | |
fidaxomicin systemic (Pro) Brand name: Dificid |
20 reviews | |
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective). |
See also
Medical conditions treated or associated with macrolides:
- Babesiosis
- Bacterial Endocarditis Prevention
- Bacterial Infection
- Bartonellosis
- Bowel Preparation
- Bronchitis
- Bullous Pemphigoid
- Campylobacter Gastroenteritis
- Cervicitis
- Chancroid
- Chlamydia Infection
- Clostridioides difficile Infection
- COPD, Acute
- Cystic Fibrosis
- Dental Abscess
- Gonococcal Infection, Uncomplicated
- Granuloma Inguinale
- Helicobacter Pylori Infection
- Legionella Pneumonia
- Lyme Disease
- Lyme Disease, Erythema Chronicum Migrans
- Lymphogranuloma Venereum
- Middle Ear Infections
- Mycobacterium avium-intracellulare, Prophylaxis
- Mycobacterium avium-intracellulare, Treatment
- Mycoplasma Pneumonia
- Nongonococcal Urethritis
- Ocular Rosacea
- Pelvic Inflammatory Disease
- Pemphigoid
- Pertussis
- Pertussis Prophylaxis
- Pharyngitis
- Pneumonia
- Rheumatic Fever Prophylaxis
- Sinusitis
- Skin and Structure Infection
- Skin or Soft Tissue Infection
- STD Prophylaxis
- Strep Throat
- Streptococcal Infection
- Syphilis, Early
- Tonsillitis/Pharyngitis
- Toxoplasmosis
- Typhoid Fever
- Upper Respiratory Tract Infection
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.