Drug Interaction Report
3 potential interactions and/or warnings found for the following 2 drugs:
- Advil PM (diphenhydramine / ibuprofen)
- aminolevulinic acid
Interactions between your drugs
ibuprofen aminolevulinic acid
Applies to: Advil PM (diphenhydramine / ibuprofen), aminolevulinic acid
Aminolevulinic acid sensitizes your skin to bright lights, and combining it with other medications that can also have this effect (i.E., photosensitivity) such as ibuprofen may increase the risk of a severe sunburn. In general, it is recommended that other potentially photosensitizing medications be avoided for 24 hours before and after taking aminolevulinic acid. There have also been suggestions to avoid these medications for up to 2 weeks afterwards, although it may not be feasible to interrupt some treatments for that long, especially if they are medically necessary. Check with your doctor to see if you should temporarily withhold any of your medications before and after taking aminolevulinic acid. Following treatment, you should avoid exposure of the eyes and skin to sunlight or bright indoor lights for 48 hours. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food/lifestyle interactions
ibuprofen food/lifestyle
Applies to: Advil PM (diphenhydramine / ibuprofen)
Ask your doctor before using ibuprofen together with ethanol (alcohol). Do not drink alcohol while taking ibuprofen. Alcohol can increase your risk of stomach bleeding caused by ibuprofen. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
diphenhydrAMINE food/lifestyle
Applies to: Advil PM (diphenhydramine / ibuprofen)
Ask your doctor before using diphenhydrAMINE together with ethanol (alcohol). Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking diphenhydrAMINE. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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