Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- danazol
- retapamulin topical
Interactions between your drugs
danazol retapamulin topical
Applies to: danazol, retapamulin topical
Coadministration with inhibitors of CYP450 3A4 may increase the plasma concentrations of retapamulin, which is primarily metabolized by the isoenzyme. In healthy adult males, coadministration of the potent CYP450 3A4 inhibitor ketoconazole (200 mg orally twice a day) increased the peak plasma concentration (Cmax) and area under the concentration-time curve (AUC) of retapamulin by 81% following topical application of retapamulin ointment 1% on abraded skin. However, dosage adjustments are not necessary due to the low systemic exposure to retapamulin following topical application.
References (1)
- (2007) "Product Information. Altabax (retapamulin topical)." GlaxoSmithKline
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Report options
- Switch to consumer interaction data
- Email this report to a friend, doctor, or patient
- Ask questions, find answers
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Eligard
Eligard (leuprolide) reduces levels of testosterone and is used to treat prostate cancer. Includes ...
Provera
Provera is used for abnormal uterine bleeding, amenorrhea, birth control, endometrial cancer ...
Ubrelvy
Ubrelvy (ubrogepant) tablets are used for the acute treatment of migraine. Includes Ubrelvy side ...
Depo Provera
Depo-Provera is used as contraception to prevent pregnancy. It is also used to reduce pain cause by ...
Lupron Depot
Lupron Depot (leuprolide acetate) and Lupron Depot-Ped are prescription hormonal injections used to ...
Sprintec
Sprintec is used for abnormal uterine bleeding, birth control, endometriosis, gonadotropin ...
Zoladex
Zoladex (goserelin) is used to treat endometriosis and breast cancer in women and prostate cancer ...
Ortho Tri-Cyclen
Ortho Tri-Cyclen (ethinyl estradiol and norgestimate) is used as a contraceptive to prevent ...
Tri-Sprintec
Tri-Sprintec is used for abnormal uterine bleeding, acne, birth control, endometriosis ...
Learn more
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Check Interactions
To view an interaction report containing 4 (or more) medications, please sign in or create an account.
Save Interactions List
Sign in to your account to save this drug interaction list.