Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- chloramphenicol
- Cleocin Phosphate ADD-Vantage (clindamycin)
Interactions between your drugs
chloramphenicol clindamycin
Applies to: chloramphenicol, Cleocin Phosphate ADD-Vantage (clindamycin)
Consumer information for this interaction is not currently available.
MONITOR: Chloramphenicol, erythromycin, lincomycin, and/or clindamycin may antagonize each other's bactericidal effects if used concomitantly. Lincomycin derivatives, erythromycin and chloramphenicol have antagonistic effects in vitro. The mechanism is competitive binding of the 50S ribosomal subunit.
MANAGEMENT: Until more data are available, the possibility of antagonism should be considered, and patients should be monitored for altered therapeutic effect of either antibiotic.
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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