Drug Interaction Report

If you are currently being treated with carvedilol, let your doctor know before you receive amifostine. Combining these medications may have additive effects in lowering your blood pressure. Depending on your condition, your doctor may want you to discontinue carvedilol for 24 hours before you receive treatment with amifostine, and your blood pressure will need to be monitored closely during and after the treatment. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. Contact your doctor if you develop these symptoms and they do not go away after a few hours, or they become troublesome. You should avoid rising abruptly from a sitting or lying position until you know how these medications affect you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.