Drug Interaction Report
3 potential interactions and/or warnings found for the following 2 drugs:
- fezolinetant
- Ogen 2.5 (estropipate)
Interactions between your drugs
estropipate fezolinetant
Applies to: Ogen 2.5 (estropipate), fezolinetant
Consumer information for this interaction is not currently available.
GENERALLY AVOID: The concurrent use of fezolinetant with systemic estrogen hormone replacement therapy has not been evaluated in prospective clinical trials. Safety and efficacy of this combination are unknown. However, the concomitant use of vaginal estrogen preparations was excluded from this warning in the product labeling for Australia and the United Kingdom.
MANAGEMENT: Due to the lack of clinical data, use of fezolinetant with systemic estrogen-containing hormone replacement therapy is not recommended. Vaginal estrogen preparations may be used according to some authorities.
Drug and food interactions
fezolinetant food
Applies to: fezolinetant
Consuming food or beverages that contain caffeine (e.G., chocolate, coffee, cola drinks, energy drinks, tea) is not recommended while taking fezolinetant. Caffeine may significantly increase the levels of fezolinetant in the blood. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
estropipate food
Applies to: Ogen 2.5 (estropipate)
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Report options
- Switch to professional interaction data
- Email this report to a friend, doctor, or patient
- Ask questions, find answers
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Paxil
Paxil is used to treat depression, obsessive-compulsive disorder and anxiety. Learn about side ...
Veozah
Veozah (fezolinetant) is used for the treatment of moderate to severe vasomotor symptoms (VMS) ...
Botox
Botox is used for cosmetic purposes and to treat overactive bladder symptoms, urinary incontinence ...
Bijuva
Bijuva (estradiol and progesterone) is used to reduce moderate to severe hot flashes in menopausal ...
Paxil CR
Paxil CR is used for anxiety, depression, dysautonomia, generalized anxiety disorder, major ...
Duavee
Duavee (bazedoxifene/conjugated estrogens) is used to treat hot flashes and prevent postmenopausal ...
EEMT
EEMT is used for hot flashes, menopausal disorders, postmenopausal symptoms
Megace ES
Megace ES (megestrol) is used to treat loss of appetite, weight loss and advanced breast and ...
Learn more
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Check Interactions
To view an interaction report containing 4 (or more) medications, please sign in or create an account.
Save Interactions List
Sign in to your account to save this drug interaction list.