Drug Interaction Report

Lactitol may affect the absorption of other medications that you take by mouth. In some cases, this may affect how well and/or how fast those medications work, or it may make no difference. In general, other oral medications should be taken 2 hours before or 2 hours after you take lactitol unless otherwise directed by your doctor. Talk to a healthcare provider if you have any questions or concerns and contact your doctor if your symptoms worsen or your condition changes. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Taking linaclotide with food may increase gastrointestinal side effects such as diarrhea, abdominal pain, and gas. The absorption of any other oral medication you may take can be affected if you develop frequent or severe diarrhea. To reduce the risk of gastrointestinal intolerance, linaclotide should be taken on an empty stomach at least 30 minutes prior to the first meal of the day. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.