Drug Interaction Report

Food may reduce the absorption and blood levels of eltrombopag. In addition, minerals such as aluminum, calcium, iron, magnesium, and zinc can also interfere with eltrombopag absorption into the bloodstream, which may make the medication less effective in treating your condition. You should take eltrombopag on an empty stomach one hour before or two hours after a meal. Eltrombopag should also be taken at least 2 hours before or 4 hours after products like antacids, mineral supplements, dairy products, and fortified juices. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Taking avatrombopag with food helps ensure consistent absorption of the medication into the blood stream. You should take each dose of avatrombopag with food at the same time everyday.

The recommended maximum number of medicines in the 'platelet-stimulating agents' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'platelet-stimulating agents' category:

• Doptelet (avatrombopag)
• Promacta (eltrombopag)

Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.