Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- apalutamide
- capromab pendetide
Interactions between your drugs
capromab pendetide apalutamide
Applies to: capromab pendetide, apalutamide
GENERALLY AVOID: The effect of surgical and/or medical androgen ablation on the imaging performance of Indium In 111 capromab pendetide has not been evaluated. Preliminary data suggest that hormone ablation may increase expression of Prostate Specific Membrane Antigen (PSMA)--the target of capromab pendetide--and decrease tumor expression of prostate specific antigen (PSA).
MANAGEMENT: Until more data are available, concomitant use of Indium In 111 capromab pendetide in patients treated with androgen ablation therapy is not recommended.
References (1)
- (2015) "Product Information. ProstaScint (capromab pendetide)." Aytu Therapeutics, LLC
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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