Drug Interaction Report
2 potential interactions and/or warnings found for the following 2 drugs:
- Alka-Seltzer Heartburn Relief Lemon Lime (citric acid/sodium bicarbonate)
- sparfloxacin
Interactions between your drugs
sodium bicarbonate sparfloxacin
Applies to: Alka-Seltzer Heartburn Relief Lemon Lime (citric acid/sodium bicarbonate), sparfloxacin
Consumer information for this interaction is not currently available.
GENERALLY AVOID: Urinary alkalinizers such as citrates may decrease the solubility of fluoroquinolones in the urine and increase the risk of crystalluria.
MANAGEMENT: Concomitant use should generally be avoided. Patients receiving this combination should be monitored for signs of renal toxicity and crystalluria.
citric acid sparfloxacin
Applies to: Alka-Seltzer Heartburn Relief Lemon Lime (citric acid/sodium bicarbonate), sparfloxacin
Talk to your doctor before using citric acid together with sparfloxacin. Citric acid can change the acidity of your urine, which may cause sparfloxacin to crystallize and form stones. This may also occur if you are dehydrated, so you should drink plenty of fluids during treatment with sparfloxacin. Let your doctor know if you experience flank pain, painful urination, or blood in the urine. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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