Drug Interaction Report
2 potential interactions and/or warnings found for the following 2 drugs:
- penicillin g potassium
- Probenecid and Colchicine (colchicine / probenecid)
Interactions between your drugs
probenecid penicillin G potassium
Applies to: Probenecid and Colchicine (colchicine / probenecid), penicillin g potassium
Information for this minor interaction is available on the professional version.
Drug and food interactions
colchicine food
Applies to: Probenecid and Colchicine (colchicine / probenecid)
Drinking large amounts of grapefruit juice can increase your blood levels of colchicine to dangerous levels. You should avoid the consumption of grapefruit or grapefruit juice during treatment with colchicine. Let your doctor know if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet, as these may be early symptoms of colchicine toxicity.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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