Drug Interaction Report
2 potential interactions and/or warnings found for the following 2 drugs:
- Erivedge (vismodegib)
- sorafenib
Interactions between your drugs
SORAfenib vismodegib
Applies to: sorafenib, Erivedge (vismodegib)
SORAfenib may increase the blood levels and effects of vismodegib. This may increase the risk and/or severity of side effects such as muscle spasm, hair loss, taste disturbances, weight loss, fatigue, nausea, vomiting, diarrhea, decreased appetite, constipation, and joint pain. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
SORAfenib food
Applies to: sorafenib
You may experience reduced absorption of SORAfenib in the presence of food. Take SORAfenib on an empty stomach 1 hour before or 2 hours after a meal unless otherwise directed by your doctor. This will make it easier for your body to absorb the medication.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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