Drug Interaction Report
3 potential interactions and/or warnings found for the following 2 drugs:
- Hismanal (astemizole)
- mifepristone
Interactions between your drugs
astemizole miFEPRIStone
Applies to: Hismanal (astemizole), mifepristone
Talk to your doctor before using astemizole together with miFEPRIStone. Combining these medications may significantly increase the blood levels of astemizole, which may increase the risk and/or severity of side effects. Your doctor may be able to prescribe alternatives that do not interact, or you may need to briefly stop using astemizole while you are being treated with miFEPRIStone. In addition, because miFEPRIStone is cleared slowly from the body, the interaction may occur even after you have stopped taking it for a while. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
astemizole food
Applies to: Hismanal (astemizole)
Astemizole is no longer on the market in the US. Do not take astemizole with any other medication, food, or beverage.
miFEPRIStone food
Applies to: mifepristone
Food increases the blood levels of this medication. If you are only receiving one or two doses, you may take it without regard to meals. However, if you are receiving the medication for long-term treatment, you should take it with food at the same time everyday to maintain consistent blood levels and effects. Avoid consuming grapefruit or grapefruit juice during treatment, as it may increase blood levels of the medication to undesirable levels and increase the risk of side effects, including headache, dizziness, fatigue, nausea, vomiting, cramping, diarrhea, hypokalemia (low blood potassium), fluid retention, swelling, and high blood pressure. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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