Drug Interaction Report
5 potential interactions and/or warnings found for the following 2 drugs:
- Bactrim DS (sulfamethoxazole / trimethoprim)
- papaverine / phentolamine
Interactions between your drugs
papaverine phentolamine
Applies to: papaverine / phentolamine, papaverine / phentolamine
Using papaverine and phentolamine together may lead to increased side effects, such as low blood pressure, dizziness, fainting, and/or priapism (prolonged and painful erection unrelated to sexual activity). Your doctor may already be aware of the risks but has determined that this is the best course of treatment for you, has taken appropriate precautions, and is monitoring you closely for any potential complications. Seek immediate medical attention if you experience an erection that lasts for more than 4 hours. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
sulfamethoxazole papaverine
Applies to: Bactrim DS (sulfamethoxazole / trimethoprim), papaverine / phentolamine
Information for this minor interaction is available on the professional version.
Drug and food interactions
sulfamethoxazole food
Applies to: Bactrim DS (sulfamethoxazole / trimethoprim)
Ask your doctor before using sulfamethoxazole together with ethanol (alcohol). Contact your doctor if you experience unpleasant side effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, or vomiting. If you experience these side effects, you may need to avoid ethanol (alcohol) while taking sulfamethoxazole. You should check your food and medicine labels to see if these products contain ethanol (alcohol). It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
papaverine food
Applies to: papaverine / phentolamine
Papaverine and ethanol (alcohol) may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
phentolamine food
Applies to: papaverine / phentolamine
Phentolamine and ethanol (alcohol) may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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