Drug Interaction Report
3 potential interactions and/or warnings found for the following 2 drugs:
- Citrocarbonate (sodium bicarbonate / sodium citrate)
- dabrafenib
Interactions between your drugs
sodium bicarbonate dabrafenib
Applies to: Citrocarbonate (sodium bicarbonate / sodium citrate), dabrafenib
Talk to your doctor before using dabrafenib together with sodium bicarbonate. By reducing stomach acid, there is a possibility that sodium bicarbonate and other medications like it may decrease the absorption of dabrafenib and make it less effective. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
sodium citrate dabrafenib
Applies to: Citrocarbonate (sodium bicarbonate / sodium citrate), dabrafenib
Talk to your doctor before using dabrafenib together with sodium citrate. By reducing stomach acid, there is a possibility that sodium citrate and other medications like it may decrease the absorption of dabrafenib and make it less effective. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
dabrafenib food
Applies to: dabrafenib
Food may delay and reduce the absorption of dabrafenib, which may lead to lower blood levels of the medication and possibly reduced effectiveness. You should take dabrafenib at least 1 hour before or 2 hours after a meal.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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