Drug Interaction Report
4 potential interactions and/or warnings found for the following 2 drugs:
- amoxicillin / clarithromycin / lansoprazole
- bosentan
Interactions between your drugs
clarithromycin lansoprazole
Applies to: amoxicillin / clarithromycin / lansoprazole, amoxicillin / clarithromycin / lansoprazole
Clarithromycin may increase the blood levels and side effects of lansoprazole in some people. Contact your doctor if you experience diarrhea or other intestinal problems. You may need a dose adjustment if you take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
clarithromycin bosentan
Applies to: amoxicillin / clarithromycin / lansoprazole, bosentan
Using bosentan together with clarithromycin may alter the blood levels of both medications. Specifically, the blood levels of clarithromycin may decrease, which may reduce its effectiveness in treating your condition. At the same time, clarithromycin may cause the blood levels of bosentan to increase. You may be more likely to experience side effects of bosentan such as nausea, vomiting, fatigue, headache, low blood pressure, fluid retention, anemia, and liver problems. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if you develop fainting; sudden, unexplained weight gain; swelling of the legs or ankles; chest pain; or difficulty breathing during treatment with these medications. You should also seek medical attention if you experience potential signs and symptoms of liver damage such as fever, rash, loss of appetite, nausea, vomiting, fatigue, upper abdominal pain, dark urine, or yellowing of the skin and eyes. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
amoxicillin clarithromycin
Applies to: amoxicillin / clarithromycin / lansoprazole, amoxicillin / clarithromycin / lansoprazole
Information for this minor interaction is available on the professional version.
Drug and food interactions
clarithromycin food
Applies to: amoxicillin / clarithromycin / lansoprazole
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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