Drug Interaction Report

Using ISOtretinoin and medroxyPROGESTERone is not recommended. ISOtretinoin can cause severe, life-threatening birth defects if the mother takes the medication during pregnancy. Even one dose of ISOtretinoin can cause major birth defects of the baby's ears, eyes, face, skull, heart, and brain. Never use ISOtretinoin if you are pregnant. You must agree in writing to use two specific forms of birth control beginning 30 days before you start taking ISOtretinoin and ending 30 days after you stop taking it. Both a primary and a secondary form of birth control must be used together. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Ask your doctor before using ISOtretinoin together with ethanol (alcohol). Do not drink alcohol while you are taking ISOtretinoin. You may have unpleasant side effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting. Check your food and medicine labels to be sure these products do not contain alcohol. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.