Drug Interaction Report
2 potential interactions and/or warnings found for the following 2 drugs:
- magnesium hydroxide
- Malarone (atovaquone / proguanil)
Interactions between your drugs
magnesium hydroxide proguanil
Applies to: magnesium hydroxide, Malarone (atovaquone / proguanil)
Using magnesium hydroxide together with proguanil can decrease the effects of proguanil. Magnesium hydroxide and proguanil should be taken at least 2 to 3 hours apart. You may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
atovaquone food
Applies to: Malarone (atovaquone / proguanil)
Food significantly enhances the absorption of atovaquone. You should take each dose of atovaquone at the same time each day with a meal or a milky drink. If you receive enteral nutrition (tube feeding), take atovaquone with your feeding. Taking it on an empty stomach may lead to inadequate blood levels and reduced effectiveness of the medication. Talk to your doctor if you have questions or have difficulty taking atovaquone with food.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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