Drug Interaction Report

Antibiotics such as levoFLOXacin may reduce the effects of estradiol in some women. If you are using estradiol for birth control, you may be at increased risk for pregnancy or breakthrough bleeding. Be sure to alert your doctor if you are having any vomiting and/or diarrhea as this too can impact how well estradiol works. Talk to your doctor or pharmacist to determine if you should use an alternative or additional form of birth control during or after treatment with levoFLOXacin. In addition, some birth control preparations may include "placebo" non-hormonal pills that contain iron. If you are taking these iron-containing pills during treatment with levoFLOXacin, you should separate the dosing times by several hours so that the iron does not interfere with absorption of the antibiotic. Ask your doctor or pharmacist for information on when best to take these medications. If you are using estradiol for a purpose other than birth control, please let your doctor know if you have any questions or notice any changes in how well estradiol is working. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

When levoFLOXacin as the oral solution is given with enteral (tube) feedings, levoFLOXacin may not work as well. You could interrupt the feeding for 1 hour before and 2 hours after the levoFLOXacin dose. However, this still may not entirely avoid the interaction and may not always be feasible. LevoFLOXacin oral tablets may be taken without regard to food. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Information for this minor interaction is available on the professional version.