Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- gemfibrozil
- Welchol (colesevelam)
Interactions between your drugs
gemfibrozil colesevelam
Applies to: gemfibrozil, Welchol (colesevelam)
ADJUST DOSING INTERVAL: Bile acid sequestrants may bind to and decrease the gastrointestinal absorption of gemfibrozil.
MANAGEMENT: Gemfibrozil and bile acid sequestrants should be taken at least 2 hours apart.
References (5)
- Forland SC, Feng Y, Cutler RE (1990) "Apparent reduced absorption of gemfibrozil when given with colestipol." J Clin Pharmacol, 30, p. 29-32
- Lozada A, Dujovne CA (1994) "Drug interactions with fibric acids." Pharmacol Ther, 63, p. 163-76
- Cerner Multum, Inc. "UK Summary of Product Characteristics."
- Canadian Pharmacists Association (2006) e-CPS. http://www.pharmacists.ca/function/Subscriptions/ecps.cfm?link=eCPS_quikLink
- Cerner Multum, Inc. "Australian Product Information."
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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