Drug Interaction Report
4 potential interactions and/or warnings found for the following 2 drugs:
- ethinyl estradiol / norelgestromin
- Provera (medroxyprogesterone)
Interactions between your drugs
No drug ⬌ drug interactions were found between the drugs in your list. However, this does not necessarily mean no drug interactions exist. Always consult your healthcare provider.
Drug and food interactions
ethinyl estradiol food
Applies to: ethinyl estradiol / norelgestromin
Consumer information for this interaction is not currently available.
MONITOR: Coadministration of ethinyl estradiol may increase the plasma concentrations of drugs that are primarily metabolized by CYP450 1A2. In a study of 30 healthy volunteers administered the CYP450 1A2 substrate tizanidine, the systemic exposure (AUC) of tizanidine was 3.9 times greater in women using an oral contraceptive containing ethinyl estradiol.
MANAGEMENT: Patients should be monitored for increased adverse effects of the CYP450 1A2 substrate during concomitant use with ethinyl estradiol. Product labeling for the specific CYP450 1A2 substrate should be consulted for additional recommendations.
ethinyl estradiol food
Applies to: ethinyl estradiol / norelgestromin
Information for this minor interaction is available on the professional version.
ethinyl estradiol food
Applies to: ethinyl estradiol / norelgestromin
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.
Progestins
Therapeutic duplication
The recommended maximum number of medicines in the 'progestins' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'progestins' category:
- ethinyl estradiol / norelgestromin
- Provera (medroxyprogesterone)
Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.
Report options
- Switch to professional interaction data
- Email this report to a friend, doctor, or patient
- Ask questions, find answers
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Mirena
Mirena (levonorgestrel) is a plastic intrauterine device placed in the uterus and is used to ...
Provera
Provera is used for abnormal uterine bleeding, amenorrhea, birth control, endometrial cancer ...
Botox
Botox is used for cosmetic purposes and to treat overactive bladder symptoms, urinary incontinence ...
Depo Provera
Depo-Provera is used as contraception to prevent pregnancy. It is also used to reduce pain cause by ...
Nexplanon
Nexplanon is a long-term, reversible birth control implant that lasts for three years. Learn about ...
Sprintec
Sprintec is used for abnormal uterine bleeding, birth control, endometriosis, gonadotropin ...
Yaz
Yaz (drospirenone and ethinyl estradiol) is used as a contraceptive to prevent pregnancy. Includes ...
Slynd
Slynd (drospirenone) is a birth control pill used for the prevention of pregnancy. Includes Slynd ...
Lo Loestrin Fe
Lo Loestrin Fe (ethinyl estradiol and norethindrone acetate) birth control tablets are used to ...
Learn more
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Check Interactions
To view an interaction report containing 4 (or more) medications, please sign in or create an account.
Save Interactions List
Sign in to your account to save this drug interaction list.