Ziv-aflibercept and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with ziv-aflibercept.
Ziv-Aflibercept High Blood Pressure (Hypertension)
Moderate Potential Hazard, Moderate plausibility
ziv-aflibercept - hypertension
The use of ziv-aflibercept increases the risk of Grade 3-4 hypertension. It is recommended to monitor blood pressure every two weeks or more frequently as clinically indicated during treatment. Patients should be treated with appropriate antihypertensive therapy and continue monitoring blood pressure regularly. Care should be exercised when treating patients with preexisting hypertension. Temporarily suspend treatment in patients with uncontrolled hypertension until controlled and permanently reduce the dose to 2 mg per kg for subsequent cycles. Discontinue therapy with ziv-aflibercept in patients with hypertensive crisis or hypertensive encephalopathy.
References (1)
- (2012) "Product Information. Zaltrap (ziv-aflibercept)." sanofi-aventis
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Ziv-aflibercept drug interactions
There are 180 drug interactions with ziv-aflibercept.
Ziv-aflibercept disease interactions
There are 6 disease interactions with ziv-aflibercept which include:
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- During pregnancy
- Drug class: VEGF/VEGFR inhibitors
- Breastfeeding
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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