Ziv-aflibercept Disease Interactions
There is 1 disease interaction with ziv-aflibercept:
Ziv-Aflibercept (Includes Ziv-aflibercept) ↔ Hemorrhage
Severe Potential Hazard, Moderate plausibility
Applies to: Gastrointestinal Perforation, Bleeding
Ziv-aflibercept can impair wound healing, cause gastrointestinal (GI) perforation, and cause severe and sometimes fatal hemorrhages including GI hemorrhage. It is recommended to suspend the use of ziv-aflibercept for at least 4 weeks prior to elective surgery and do not resume treatment for at least 4 weeks following major surgery and until the surgical wound is fully healed. Monitor patients for signs and symptoms of GI perforation. It is recommended to discontinue the use of this agent in patients who experience GI perforation or in patients with compromised wound healing.
ziv-aflibercept drug Interactions
There are 107 drug interactions with ziv-aflibercept
More about ziv-aflibercept
- Ziv-aflibercept Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Drug class: VEGF/VEGFR inhibitors
Related treatment guides
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
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