Thiotepa and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with thiotepa.
Nicotine Thiotepa
Minor Drug Interaction
Coadministration of thiotepa may increase plasma concentrations of drugs that are primarily metabolized by CYP450 2B6. Thiotepa has been shown to be a weak inhibitor of CYP450 2B6 in vitro, although drug interactions studies are not available, and the clinical significance is unknown. Product labeling for the specific CYP450 2B6 substrate should be consulted for additional recommendations and monitoring for increased adverse effects when used concomitantly with thiotepa may be warranted.
References (4)
- (2023) "Product Information. Thiotepa (thiotepa)." Meitheal Pharmaceuticals Inc.
- (2023) "Product Information. Tepadina (thiotepa)." Link Medical Products Pty Ltd T/A Link Pharmaceuticals, 3
- (2022) "Product Information. Thiotepa (thiotepa)." MSN Laboratories Europe Ltd
- (2021) "Product Information. Tepadina (thiotepa)." Adienne SA
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Thiotepa drug interactions
There are 465 drug interactions with thiotepa.
Thiotepa disease interactions
There are 4 disease interactions with thiotepa which include:
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
