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Arakoda and Alcohol/Food Interactions

There is 1 alcohol/food/lifestyle interaction with Arakoda (tafenoquine).

Moderate

Tafenoquine Food

Moderate Food Interaction

ADJUST DOSING INTERVAL: Food enhances the oral bioavailability of tafenoquine. According to the manufacturer, tafenoquine peak plasma concentration (Cmax) and systemic exposure (AUC) increased by 31% and 41%, respectively, when administered as an investigational capsule formulation with a high-calorie, high-fat meal (approximately 1000 calories; 15% protein, 25% carbohydrate, 60% fat) relative to the fasted state.

MANAGEMENT: Tafenoquine should be administered with food.

References

  1. (2018) "Product Information. Krintafel (tafenoquine)." GlaxoSmithKline

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Arakoda drug interactions

There are 35 drug interactions with Arakoda (tafenoquine).

Arakoda disease interactions

There are 3 disease interactions with Arakoda (tafenoquine) which include:

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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