Arakoda Disease Interactions
There are 3 disease interactions with Arakoda (tafenoquine).
Tafenoquine (applies to Arakoda) G6PD deficiency
Major Potential Hazard, Moderate plausibility. Applicable conditions: G-6-PD Deficiency
Tafenoquine is contraindicated in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency or unknown G6PD status due to the risk of hemolytic anemia. All patients must be tested for G6PD deficiency prior to prescribing tafenoquine.
Tafenoquine (applies to Arakoda) psychotic disorders
Major Potential Hazard, Moderate plausibility. Applicable conditions: Psychosis
Tafenoquine is contraindicated in patients with a history of psychotic disorders or current psychotic symptoms such as hallucinations, delusions, and/or grossly disorganized behavior. If psychotic symptoms occur (hallucinations, delusions), consider discontinuation of tafenoquine and a prompt evaluation by a mental health professional as soon as possible. Other psychiatric symptoms, such as changes in mood, anxiety, insomnia, and nightmares, should be promptly evaluated by a medical professional if they are moderate and last more than three days or are severe.
Tafenoquine (applies to Arakoda) hepatic/renal
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction, Liver Disease
The pharmacokinetics of tafenoquine have not been studied in patients with renal or hepatic impairment. If tafenoquine is administered to such patients, close monitoring for adverse reactions is needed.
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Arakoda drug interactions
There are 36 drug interactions with Arakoda (tafenoquine).
Arakoda alcohol/food interactions
There is 1 alcohol/food interaction with Arakoda (tafenoquine).
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.