Nuplazid and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with Nuplazid (pimavanserin).
Pimavanserin Obesity
Moderate Potential Hazard, Moderate plausibility
atypical antipsychotic agents - hyperglycemia/diabetes
Hyperglycemia, in some cases extreme and associated with ketoacidosis or hyperosmolar coma or death, has been reported with the use of atypical antipsychotic agents. Patients with diabetes should be monitored for worsening control of blood glucose when treated with these agents. It is recommended that patients with risk factors for diabetes mellitus starting treatment with atypical antipsychotics should undergo fasting blood glucose testing at the beginning of treatment, and periodically thereafter. Any patient treated with atypical antipsychotics should be monitored for symptoms of hyperglycemia including polydipsia, polyuria, polyphagia, and weakness. Patients who develop symptoms of hyperglycemia during treatment with atypical antipsychotics should undergo fasting blood glucose testing. In some cases, hyperglycemia has resolved when treatment with these agents was discontinued; however, some patients required continuation of anti-diabetic treatment despite discontinuation of the atypical antipsychotic drug.
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Nuplazid drug interactions
There are 369 drug interactions with Nuplazid (pimavanserin).
Nuplazid disease interactions
There are 9 disease interactions with Nuplazid (pimavanserin) which include:
- dementia
- NMS
- hepatic impairment
- QT prolongation
- seizure
- hematologic abnormalities
- hyperglycemia/diabetes
- hyperprolactinemia
- renal impairment
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Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
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