Nuplazid (pimavanserin) and Alcohol / Food Interactions
There is 1 alcohol/food/lifestyle interaction with Nuplazid (pimavanserin):
Moderate Potential Hazard, Moderate plausibility
atypical antipsychotic agents - hyperglycemia/diabetes
Hyperglycemia, in some cases extreme and associated with ketoacidosis or hyperosmolar coma or death, has been reported with the use of atypical antipsychotic agents. Patients with diabetes should be monitored for worsening control of blood glucose when treated with these agents. It is recommended that patients with risk factors for diabetes mellitus starting treatment with atypical antipsychotics should undergo fasting blood glucose testing at the beginning of treatment, and periodically thereafter. Any patient treated with atypical antipsychotics should be monitored for symptoms of hyperglycemia including polydipsia, polyuria, polyphagia, and weakness. Patients who develop symptoms of hyperglycemia during treatment with atypical antipsychotics should undergo fasting blood glucose testing. In some cases, hyperglycemia has resolved when treatment with these agents was discontinued; however, some patients required continuation of anti-diabetic treatment despite discontinuation of the atypical antipsychotic drug.
Nuplazid (pimavanserin) drug Interactions
There are 358 drug interactions with Nuplazid (pimavanserin)
Nuplazid (pimavanserin) disease Interactions
There are 10 disease interactions with Nuplazid (pimavanserin) which include:
- Tardive Dyskinesia
- Hepatic Impairment
- Qt Prolongation
- Hematologic Abnormalities
- Seizure Disorders
- Renal Impairment
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
|Major||Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderate||Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minor||Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
Do not stop taking any medications without consulting your healthcare provider.
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