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Ketoconazole and Alcohol/Food Interactions

There is 1 alcohol/food/lifestyle interaction with ketoconazole.


ketoconazole Alcohol (Ethanol)

Moderate Drug Interaction

Ketoconazole may cause liver problems and using it with ethanol or products containing alcohol may increase that risk. Call your doctor immediately if you have swelling, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, as these may be signs and symptoms of liver damage. In addition, the use of ethanol or products containing alcohol during treatment with ketoconazole may trigger a disulfiram-like reaction in some patients, which includes unpleasant effects such as flushing, rash, peripheral edema, nausea, and headache. Talk to your doctor or pharmacist if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Ketoconazole drug interactions

There are 626 drug interactions with ketoconazole.

Ketoconazole disease interactions

There are 4 disease interactions with ketoconazole which include:

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.