Ketoconazole User Reviews & Ratings

Ketoconazole has an average rating of 6.4 out of 10 from a total of 21 reviews on Drugs.com. 57% of reviewers reported a positive experience, while 33% reported a negative experience.

Condition	Avg. Rating	Reviews	Compare
Vaginal Yeast Infection Off-label	5.8	7 reviews for Vaginal Yeast Infection	63 medications
Tinea Versicolor Off-label	8.0	6 reviews for Tinea Versicolor	96 medications
Dermatophytosis Off-label	7.0	2 reviews for Dermatophytosis	11 medications
Onychomycosis, Toenail Off-label	10.0	2 reviews for Onychomycosis, Toenail	20 medications
Oral Thrush Off-label	1.5	2 reviews for Oral Thrush	34 medications
Coccidioidomycosis	10.0	1 reviews for Coccidioidomycosis	8 medications
Tinea Corporis Off-label	1.0	1 reviews for Tinea Corporis	121 medications

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Reviews for Ketoconazole

sti...
Taken for 1 to 6 months
March 12, 2015

For Onychomycosis, Toenail "Took Nizoral, and my GI distress symptoms resolved, all toenails cleared of fungus growth symptoms, including big toenails that fell off, and new healthy ones replaced, and scalp cleared up from dandruff."

10 / 10

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29 Report

Can...
Taken for less than 1 month
October 13, 2019

For Vaginal Yeast Infection "Made me a bit nauseous off and on for the first week, then intense, debilitating stomach cramps and diarrhea on the 8th or 9th day of use. Also did not cure the yeast infection. At first, it seemed like it was working, then symptoms came back worse than before."

1 / 10

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16 Report

Anonymous
June 26, 2011

For Vaginal Yeast Infection "I have Lyme disease, so I got a yeast infection from antibiotic usage. My yeast infection is nothing like you will find. Basically, it just feels like rug burn on the head of my penis. Unfortunately, it rubs in my underwear when I walk around, so it's VERY ANNOYING. I was given Diflucan, and it gave me head pressure, so they gave me Ketoconazole, and it's my second/third day on it. I have NOT seen any substantial improvements. Yes, it's helped, but this should work faster."

3 / 10

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20 Report

Frequently asked questions

What is ketoconazole cream used for?

Aus...
Taken for less than 1 month
February 20, 2022

For Vaginal Yeast Infection "This drug was one of the only oral antifungals I wasn’t allergic to and worked amazingly well to clear all yeast infections within the ten-day treatment on the lowest dose. Very disappointed that it was removed from use in Australia because some people on long-term use of it got serious side effects. You’d think they’d just restrict all long-term use rather than remove a very good treatment tablet. Now I have nothing to take or apply that I’m not allergic to or have extreme side effects with."

10 / 10

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6 Report

ac2...
October 20, 2015

Nizoral (ketoconazole) for Tinea Versicolor "I have a severe case of tinea versicolor, and I have tried several over-the-counter remedies as well as a couple of prescriptions. I read the other comments on here, was hopeful based on their experience, so I asked my doctor for it! WORST IDEA EVER!!!! I was also on a few other medications at the same time for ADD and depression/anxiety. The Nizoral had a completely unexpected interaction and caused me to go crazy. No, really-I mean hallucinating, talking to inanimate objects, thinking my car and trees and such things were alive... absolutely out-of-my-mind nuts. It was terrifying. PLEASE!!-if you are going to try Nizoral and you're on any other medication, I beg you to stay in close and honest communication with your doctor. PLEASE BE CAREFUL!!!"

1 / 10

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14 Report

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Sha...
Taken for less than 1 month
March 26, 2013

"I only started this medication 6 hours ago from writing this, and my ears are clearing up, my neck is less stiff, but the bladder is still a bit irritated, so it might take a bit longer for my bladder irritation. 3 years ago, I started suffering pain, jaw problems, neck, bladder, bowel, throat, tonsils removed, MRI on jaw clicking. I do have H. pylori, dry skin, depression, anxiety, intestine problems, and just all-out hell. To find out it is possibly a fungal infection is WOW. WHY DON'T DOCTORS TEST FOR THIS MORE? Meds: Oxycodone, Methadone, Para/Codeine, Valium, Xanax, and the list goes on. Overall this has helped me in 6 hours more than what has in 3 years. Post back in 2 weeks to let you know how it went."

10 / 10

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13 Report

Ali...
Taken for 6 months to 1 year
July 1, 2022

For Tinea Versicolor "This cream really works! My Dr had prescribed both Nystop powder and cream, which didn't help. I also tried apple cider vinegar, tea tree oil and antifungal soap. The ketoconazole was the only thing that cleared up my rash. I had no adverse side effects."

10 / 10

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3 Report

Eur...
Taken for 1 to 2 years
January 6, 2016

For Dermatophytosis "I started using treatments for a skin rash that suddenly started appearing on my body. After using a box which is equal to 10 tablets, I realized the rashes were disappearing, so I stopped using it. Several days or weeks later, the rashes had started coming again. Now I started taking it, and I'm having pretty bad side effects, but I can see it's working. However, side effects on my liver and a little swelling of my tongue too. Should I stop using it and start using it in its correct way-that's one tablet (200 mg) a day for 6 months?"

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7 Report

Mat...
Taken for 1 to 6 months
June 16, 2020

"Had such high cortisol that docs thought I had a tumor (Cushing's Disease), but the MRI didn't turn one up so they diagnosed me with pseudo-Cushing's, a wastebasket term for inexplicably high cortisol. Pseudo-C wrecked my whole body: insomnia, testosterone below 300, zero sex drive, low immunity, gut issues, muscle wasting, low metabolism, visceral fat, physical anxiety (anxiety that comes from your body, not your mind), hypertension (I'm a scrawny vegan! WTF), sickest I've ever been. Ketoconazole smashed the cortisol, so much so that I ended up with LOW cortisol and had such bad nausea that I had to stop. It did work, but it replaced the old problems with new ones: erection issues , new insomnia, nausea nausea nausea, no appetite (had to force myself to eat, and only wanted yogurt), constipation, lethargy. Most of those are low cortisol, but the erection problems, even lower testosterone, and nausea are all ketoconazole. It worked, but at a high price:"

6 / 10

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4 Report

Rh1...
Taken for less than 1 month
March 5, 2018

For Oral Thrush "Avoid!! Needed for a really bad oral thrush infection from antibiotics and ended up gastritis and liver problems! I am a health 27 year old female and have never had anything wrong with my liver, ever! I immediately stopped using once I started to endure side effects after 5 days of 2x daily. Please use other methods. I have never been in such pain in my life and had to go to urgent care!!"

2 / 10

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4 Report

Anonymous
Taken for less than 1 month
October 18, 2021

"You have to be careful taking this medicine! And don't take it for a long. I took this as hormone balancing treatment. I am mid-thirty's female and I had really high cortisol due to chronic stress, which caused cushings like symptomps. I had buffalo hump fat. Belly fat. Striations /stretch marks on my belly, thighs and love handles while having skinny arms and legs. I started to grow masculine hair on my face and body. Acne on my lower face. But the worst part was the horrible morning anxiety ( when cortisol peaks upon waking). My body was buzzing with anxiety and I had an anxiety "pit" in my stomach. I was not able to think straight, I was so wired with cortisol. Cortisol was destroying my body. I even started losing my hair on my head. So for 2 weeks ONLY I took 200mg Ketokonazole before bed. This was in combinaton with Levothyroxine/Thyronorm 12mcg in the morning to balance lower thyroid. Buplerum liver cleanse to counteract. I was miraculously anxiety free. It was great"

10 / 10

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2 Report

rhe...
Taken for less than 1 month
March 5, 2018

For Oral Thrush "Do not take! I am a healthy 27 year old female that had a bad case of oral thrush due to an antibiotic and instantly started experiencing side pain. I waited five days before experiencing pain excruciating enough to make me chose childbirth over this pain. I went to urgent care and was diagnosed with gastritis because of this medication and it messed my liver up! Do not take!! There are better options!!!"

1 / 10

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3 Report

Anonymous
Taken for less than 1 month
October 7, 2019

For Tinea Corporis "Well I was in Mexico and decided to go to a urologist to check if everything is ok with my balls and penis since I recently got a girlfriend and we have sex. Everything was ok but the doctor noticed some fungus on my penis so he prescribed me with some creme and these pills for medication for 3 weeks straight. Well I took them for 3 days then decided to go on google and found out a lot of negativity regarding these mediciations. I do not want to mess up my liver. I read a lot of side effects that could damage the liver. So I decided to stop using these pills."

1 / 10

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2 Report

Car...
Taken for 1 to 6 months
October 14, 2020

For Coccidioidomycosis "I have been using ketoconazole shampoo for 3 mos., scalp lesions are now dried up... I had been active since Nov. 2019 and through Oct. 2020. It works really well, except that its very drying; used coconut oil with essential oils for that (cocci. doesn't react), and they simply moved south, from inside the scalp to other parts of the body. Now, I am dealing with them in ears, sinus, neck lesion, one battle at a time, but my scalp which is very visible (due to much hair loss), is a positive. I recommend it."

10 / 10

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1 Report

Anonymous
August 30, 2021

For Tinea Versicolor "Studies support two doses of oral Nizoral eliminated tinea versicolor if > 90% of patients. Some doctors will use one dose daily for however many days but it can be rough on liver enzymes (and the liver) It will come back many times annually during humid conditions. Repeating the same regimen usually takes care of it again within days"

10 / 10

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1 Report

Anonymous
October 11, 2011

Nizoral (ketoconazole) for Vaginal Yeast Infection "Excellent for vaginal infection."

10 / 10

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53 Report

Nan...
Taken for less than 1 month
November 19, 2013

For Vaginal Yeast Infection "Using this as a treatment for yeast infection and skin infection. It has had a remarkable response to the yeast infection, but not so for the skin."

10 / 10

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34 Report

wal...
Taken for less than 1 month
July 19, 2012

Nizoral (ketoconazole) for Tinea Versicolor "My son and I both have taken Nizoral twice a day for 6 days. It cleared the issue up completely in approximately one month. However, it seems to return after a few years."

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32 Report

sub...
August 17, 2012

Nizoral (ketoconazole) for Tinea Versicolor "To be more effective, Tinea versicolor has to be treated on the inside with the pills, and on the outside with the shampoo. The dermatologist informed me of this."

10 / 10

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23 Report

tim...
April 6, 2015

For Tinea Versicolor "I experienced itching while on medication, and immediately I stopped taking it, which was after three weeks of treatment, but the tinea disappeared."

9 / 10

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9 Report

Pat...
Taken for less than 1 month
June 13, 2018

For Onychomycosis, Toenail "Currently I am taking the tablet for toenails fungus, and head dandruff. I am on day 4 I haven't seen any results yet but I think it's too soon"

10 / 10

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5 Report

Dee...
Taken for less than 1 month
September 14, 2023

For Vaginal Yeast Infection "Using it, but the symptoms seem to occur every month with thick discharge."

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1 Report

Dee...
March 7, 2021

For Vaginal Yeast Infection "I started itching more and it did not help me at all."

1 / 10

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1 Report

b0b...
Taken for 1 to 6 months
June 21, 2021

For Dermatophytosis "Foam goes flat before end of unit quantity. Shame, at $660 a can, on you."

7 / 10

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1 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.