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Florinef and Alcohol/Food Interactions

There are 2 alcohol/food/lifestyle interactions with Florinef (fludrocortisone).

Moderate

Fludrocortisone High Blood Pressure (Hypertension)

Moderate Potential Hazard, High plausibility

corticosteroids - fluid retention

Corticosteroids may cause hypernatremia, hypokalemia, fluid retention, and elevation in blood pressure. Large doses of any corticosteroid can demonstrate these effects, particularly if given for longer periods. Therapy with corticosteroids should be administered cautiously in patients with preexisting fluid retention, hypertension, congestive heart failure, and/or renal dysfunction. Dietary sodium restriction and potassium supplementation may be advisable.

References

  1. (2001) "Product Information. Hydeltrasol (prednisolone)." Merck & Co., Inc
  2. (2001) "Product Information. Deltasone (prednisone)." Pharmacia and Upjohn
  3. (2001) "Product Information. Decadron (dexamethasone)." Merck & Co., Inc
  4. (2001) "Product Information. Hydrocortone (hydrocortisone)." Merck & Co., Inc
  5. (2001) "Product Information. Medrol (methylprednisolone)." Pharmacia and Upjohn
  6. (2001) "Product Information. Florinef Acetate (fludrocortisone)." Bristol-Myers Squibb
  7. (2001) "Product Information. Cortone Acetate (cortisone)." Merck & Co., Inc
  8. (2001) "Product Information. Kenalog (triamcinolone)." Bristol-Myers Squibb
  9. (2001) "Product Information. Celestone (betamethasone)." Schering Corporation
  10. (2021) "Product Information. Emflaza (deflazacort)." PTC Therapeutics, Inc., SUPPL-5
  11. (2023) "Product Information. Agamree (vamorolone)." Santhera Pharmaceuticals (US)
View all 11 references
Moderate

Fludrocortisone High Cholesterol (Hyperlipoproteinemia, Hypertriglyceridemia, Sitosterolemia)

Moderate Potential Hazard, Moderate plausibility

corticosteroids - hyperlipidemia

Corticosteroids may elevate serum triglyceride and LDL cholesterol levels if used for longer than brief periods. Patients with preexisting hyperlipidemia may require closer monitoring during prolonged corticosteroid therapy, and adjustments made accordingly in their lipid-lowering regimen.

References

  1. Seale JP, Compton MR (1986) "Side-effects of corticosteroid agents." Med J Aust, 144, p. 139-42
  2. (2001) "Product Information. Hydeltrasol (prednisolone)." Merck & Co., Inc
  3. (2001) "Product Information. Deltasone (prednisone)." Pharmacia and Upjohn
  4. (2001) "Product Information. Decadron (dexamethasone)." Merck & Co., Inc
  5. (2001) "Product Information. Hydrocortone (hydrocortisone)." Merck & Co., Inc
  6. (2001) "Product Information. Medrol (methylprednisolone)." Pharmacia and Upjohn
  7. (2001) "Product Information. Florinef Acetate (fludrocortisone)." Bristol-Myers Squibb
  8. (2001) "Product Information. Cortone Acetate (cortisone)." Merck & Co., Inc
  9. (2001) "Product Information. Kenalog (triamcinolone)." Bristol-Myers Squibb
  10. (2001) "Product Information. Celestone (betamethasone)." Schering Corporation
View all 10 references

Florinef drug interactions

There are 570 drug interactions with Florinef (fludrocortisone).

Florinef disease interactions

There are 22 disease interactions with Florinef (fludrocortisone) which include:


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.