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Kadcyla (ado-trastuzumab emtansine) and Alcohol / Food Interactions

There is 1 alcohol/food/lifestyle interaction with Kadcyla (ado-trastuzumab emtansine):

Moderate

High Blood Pressure (Hypertension)

Moderate Potential Hazard, Moderate plausibility

HER2 inhibitors - CHF

Decreases in left ventricular ejection fraction (LVEF) have been reported with agents that block HER2 activity. Patients who have received prior anthracyclines, those who received anthracycline after stopping therapy with agents that block HER2 activity, or patients who received prior radiotherapy to the chest area may be at higher risk of decreased LVEF. Therapy with these agents should be administered cautiously in patients with prior history of heart conditions. Evaluate cardiac function before, during and upon completion of treatment. Discontinue treatment with agents that block HER2 activity as appropriate, and for a confirmed clinically significant decrease in left ventricular function, or if the LVEF has not improved or has declined further, unless the benefits for the individual patient outweigh the risks.

Kadcyla (ado-trastuzumab emtansine) drug Interactions

There are 263 drug interactions with Kadcyla (ado-trastuzumab emtansine)

Kadcyla (ado-trastuzumab emtansine) disease Interactions

There are 5 disease interactions with Kadcyla (ado-trastuzumab emtansine) which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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