Tolcapone Interactions
There are 290 drugs known to interact with tolcapone, along with 6 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 54 are major, 232 are moderate, and 4 are minor.
- View all 290 medications that may interact with tolcapone
- View tolcapone alcohol/food interactions (1)
- View tolcapone disease interactions (6)
Most frequently checked interactions
View interaction reports for tolcapone and the medicines listed below.
- Abilify (aripiprazole)
- Activase (alteplase)
- Adderall (amphetamine / dextroamphetamine)
- Adderall XR (amphetamine / dextroamphetamine)
- AndroGel (testosterone)
- Atgam (lymphocyte immune globulin, anti-thy (equine))
- Ativan (lorazepam)
- Azilect (rasagiline)
- Benadryl (diphenhydramine)
- Betapace AF (sotalol)
- BuSpar (buspirone)
- Butalbital Compound (aspirin / butalbital / caffeine)
- Cardizem SR (diltiazem)
- Catapres (clonidine)
- Celebrex (celecoxib)
- Celexa (citalopram)
- Cogentin (benztropine)
- Comirnaty (COVID-19 mRNA (Pfizer) vaccine)
- Contrave (bupropion / naltrexone)
- Crestor (rosuvastatin)
- Cuprimine (penicillamine)
- Deplin (l-methylfolate)
- Dexedrine (dextroamphetamine)
- Diamox (acetazolamide)
- Dificid (fidaxomicin)
- Duopa (carbidopa / levodopa)
- Dymista (azelastine / fluticasone nasal)
- Fentanyl Transdermal System (fentanyl)
- Fetzima (levomilnacipran)
- Givlaari (givosiran)
Tolcapone alcohol/food interactions
There is 1 alcohol/food interaction with tolcapone.
Tolcapone disease interactions
There are 6 disease interactions with tolcapone which include:
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More about tolcapone
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- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: dopaminergic antiparkinsonism agents
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
