Tolcapone Interactions
There are 290 drugs known to interact with tolcapone, along with 6 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 54 are major, 232 are moderate, and 4 are minor.
- View all 290 medications that may interact with tolcapone
- View tolcapone alcohol/food interactions (1)
- View tolcapone disease interactions (6)
Most frequently checked interactions
View interaction reports for tolcapone and the medicines listed below.
- Abilify (aripiprazole)
- Activase (alteplase)
- Adderall (amphetamine / dextroamphetamine)
- Adderall XR (amphetamine / dextroamphetamine)
- AndroGel (testosterone)
- Atgam (lymphocyte immune globulin, anti-thy (equine))
- Ativan (lorazepam)
- Azilect (rasagiline)
- Benadryl (diphenhydramine)
- Betapace AF (sotalol)
- BuSpar (buspirone)
- Butalbital Compound (aspirin / butalbital / caffeine)
- Cardizem SR (diltiazem)
- Catapres (clonidine)
- Celebrex (celecoxib)
- Celexa (citalopram)
- Cogentin (benztropine)
- Comirnaty (COVID-19 mRNA (Pfizer) vaccine)
- Contrave (bupropion / naltrexone)
- Crestor (rosuvastatin)
- Cuprimine (penicillamine)
- Deplin (l-methylfolate)
- Dexedrine (dextroamphetamine)
- Diamox (acetazolamide)
- Dificid (fidaxomicin)
- Duopa (carbidopa / levodopa)
- Dymista (azelastine / fluticasone nasal)
- Fentanyl Transdermal System (fentanyl)
- Fetzima (levomilnacipran)
- Givlaari (givosiran)
Tolcapone alcohol/food interactions
There is 1 alcohol/food interaction with tolcapone.
Tolcapone disease interactions
There are 6 disease interactions with tolcapone which include:
Report options
More about tolcapone
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- During pregnancy
- Drug class: dopaminergic antiparkinsonism agents
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Sinemet
Sinemet is used to treat symptoms of Parkinson's disease, such as muscle stiffness, tremors ...
Cogentin
Cogentin is used for extrapyramidal reaction, parkinson's disease
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Exelon
Exelon (rivastigmine) is used to treat dementia caused by Alzheimer's or Parkinson's disease ...
Gocovri
Gocovri (amantadine) is used in the treatment of Parkinson's disease. Includes Gocovri side ...
Rivastigmine
Rivastigmine systemic is used for alzheimer's disease, lewy body dementia, parkinson's disease
Amantadine
Easy-to-read patient leaflet for amantadine. Includes indications, proper use, special ...
Carbidopa/levodopa
Carbidopa/levodopa systemic is used for GTP-CH Deficiency, neuroleptic malignant syndrome ...
Pramipexole
Pramipexole systemic is used for parkinson's disease, periodic limb movement disorder, restless ...
Benztropine
Benztropine systemic is used for extrapyramidal reaction, hyperhidrosis, parkinson's disease
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
