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Pyrilamine Drug Interactions

A total of 841 drugs are known to interact with pyrilamine.

  • 47 major drug interactions
  • 789 moderate drug interactions
  • 5 minor drug interactions

Show all medications in the database that may interact with pyrilamine.

Check for interactions

Type in a drug name to check for interactions with pyrilamine.

Most frequently checked interactions

View interaction reports for pyrilamine and the medicines listed below.

  • Aceta (acetaminophen)
  • Allegra (fexofenadine)
  • Azithromycin Dose Pack (azithromycin)
  • Chlorpheniramine (Allergy) (chlorpheniramine)
  • Delsym (dextromethorphan)
  • Dextran 70 6% in 0.9% Sodium Chloride (dextran, high molecular weight)
  • Dextrose (glucose)
  • diphenhydramine (Benadryl, Banophen, Benadryl Allergy, ZzzQuil, Sleep, Unisom SleepGels, Benadryl Children's Allergy, Sominex, Dicopanol, Diphen, Sleep Tabs, Simply Sleep, Diphedryl, Diphenadryl, Quenalin, Diphenyl, Hydramine, Diphenydramine Quick Melt, Unisom SleepMelts, Nytol, Dormin, Sleepwell 2-nite, Diphenhist, 40 Winks, Diphen Cough, DPH, Calm-Aid, Sleep Tab II, Altaryl, Snooze Fast, Sominex Maximum Strength Caplet, Unisom SleepMinis, Unisom Liquid, Triaminic Thin Strips Allergy, ConRx Allergy, Buckley's Bedtime, Hyrexin, Hydramine Cough Syrup, Bydramine, Diphen AF, Aler-Dryl, Allergia-C, Benahist-10, Benahist-50, Benoject-50, Genahist, Alka-Seltzer Plus Allergy, Q-Dryl, Aller-G-Time, Sleep-Eze-3, Somnicaps, Nytol QuickCaps, Total Allergy, Trux-adryl, Valu-Dryl, Triaminic Thin Strips Cough & Runny Nose, Beldin, Belix, Vicks QlearQuil Nighttime Allergy Relief, Siladryl, Siladryl DAS, Siladyl SA, Silphen Cough, Sleep-ettes, Tusstat, Diphenylin, Hydramine Compound, Pardryl, Nervine, Nu-Med, Nytol Caplet, Compoz Nighttime Sleep Aid, Sleepinal, Help I Can't Sleep, Allermax, Diphendryl, Twilite, Banaril, Aler-Tab, Siladryl Allergy, Theraflu Thin Strips Multi Symptom, Sleep-ettes D, Uni-Tann, Q-Dryl A/F, Diphenmax, Nightime Sleepaid, Ben-Tann, Dytan, Vanamine PD, Pharbedryl, Histaprin, Z-Sleep, Tranquil Nighttime Sleep Aid, PediaCare Children's Allergy, Truxadryl, Complete Allergy Relief, Dytuss, Miles Nervine, Scot-Tussin Allergy)
  • Dulera (formoterol / mometasone)
  • Emetrol, Cherry (phosphorated carbohydrate solution)
  • Errin (norethindrone)
  • Flonase (fluticasone nasal)
  • ibuprofen (Advil, Motrin, IBU, Advil Liqui-Gels, Children's Motrin, Proprinal, Motrin IB, Childrens Ibuprofen Berry, Advil Children's, Ibuprofen PMR, Ibu-8, Rufen, IBU-200, Motrin Childrens, Advil Migraine, Caldolor, Ibu-Tab, Menadol, Midol Maximum Strength Cramp Formula, Motrin Migraine Pain, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, Motrin Pediatric, Genpril, Haltran, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, A-G Profen, Nuprin, Advil Junior Strength, Actiprofen, Addaprin, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, Motrin Junior Strength, Motrin Infant Drops, NeoProfen, Help I Have An Aching Body, Children's ElixSure IB, Advil Infant's Concentrated Drops, Cap-Profen, Advil Film-Coated)
  • loratadine (Claritin, Alavert, Claritin 24 Hour Allergy, Loratadine Reditab, Allergy Relief 24 Hour, Claritin Reditabs, Allergy Relief Tablets, Wal-itin, Children's Claritin Allergy, Children's Allergy Relief 24 Hour, Vicks QlearQuil All Day & All Night 24 Hour Allergy Relief, Help I Have Allergies, ohm Allergy Relief, Clear-Atadine, Claritin Hives Relief, Dimetapp Children's ND Non-Drowsy Allergy, Clear-Atadine Children's, Bactimicina Allergy, Tavist ND)
  • Mucinex DM (dextromethorphan / guaifenesin)
  • Osteo Bi-Flex Triple Strength (chondroitin / glucosamine)
  • pamabrom (Diurex Water Capsules, Diurex Max, Diurex Aquagels, Aqua-Ban with Pamabrom, Aqua-Ban)
  • Pamprin Maximum Pain (acetaminophen / pamabrom / pyrilamine)
  • phenylephrine (Neo-Synephrine, Sudafed PE Congestion, Suphedrine PE, Nasal Decongestant PE, Help I Have A Stuffy Nose, Sudogest PE, Dimetapp Toddler's Drops Decongestant, Vazculep, Sudafed PE Children's Nasal Decongestant, Despec-SF, Nasop12, Triaminic Thin Strips Cold with Stuffy Nose, Phenyl-T, Congest Aid II, AH-Chew D, Gilchew IR, Little Colds Decongestant, Lusonal, Contac-D, Nasop, Ricobid-D, PediaCare Children's Decongestant)
  • Singulair (montelukast)
  • Tums Regular Strength (calcium carbonate)
  • Vicodin (acetaminophen / hydrocodone)
  • Vitamin D3 (cholecalciferol)
  • Zinc (zinc sulfate)
  • Zinc 50 mg Pink (zinc sulfate)
  • Zyrtec (cetirizine)

Pyrilamine alcohol/food interactions

There is 1 alcohol/food interaction with pyrilamine

Pyrilamine disease interactions

There are 7 disease interactions with pyrilamine which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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