Tagrisso Drug Interactions
Currently displaying a list of 619 drugs known to interact with Tagrisso (osimertinib).
- 254 major drug interactions
- 316 moderate drug interactions
- 49 minor drug interactions
Medications known to interact with Tagrisso
Note: Showing generic names only.
A
- abametapir topical
- abarelix
- abemaciclib
- abiraterone
- abrocitinib
- acalabrutinib
- adagrasib
- adalimumab
- adenosine
- adenovirus vaccine
- afatinib
- albuterol
- alefacept
- alemtuzumab
- alfentanil
- alfuzosin
- alosetron
- alpelisib
- aminoglutethimide
- amiodarone
- amisulpride
- amitriptyline
- amobarbital
- amoxapine
- amprenavir
- anagrelide
- anakinra
- anthrax vaccine adsorbed
- apalutamide
- apomorphine
- aprepitant
- arformoterol
- aripiprazole
- armodafinil
- arsenic trioxide
- artesunate
- asciminib
- asenapine
- astemizole
- atazanavir
- atezolizumab
- atomoxetine
- avacopan
- avanafil
- avelumab
- azathioprine
- azithromycin
B
- baricitinib
- bcg
- bcg vaccine
- bedaquiline
- belzutifan
- bendamustine
- benzgalantamine
- bepridil
- berotralstat
- bexarotene
- bicalutamide
- bifidobacterium infantis
- bifidobacterium longum
- binimetinib
- bisacodyl
- bitolterol
- boceprevir
- bortezomib
- bosentan
- bosutinib
- brewer's yeast
- brigatinib
- buprenorphine
- buspirone
- butabarbital
- butalbital
C
- cabozantinib
- caffeine
- canakinumab
- candida albicans extract
- capivasertib
- carbamazepine
- casanthranol
- cascara sagrada
- castor oil
- cemiplimab
- cenobamate
- ceritinib
- certolizumab
- chikungunya vaccine, live (cvx 317)
- chikungunya vaccine, recombinant (cvx 329)
- chloramphenicol
- chloroquine
- chlorpromazine
- cholera vaccine
- cholera vaccine, live
- cilostazol
- cimetidine
- ciprofloxacin
- cisapride
- citalopram
- cladribine
- clarithromycin
- clofazimine
- clomipramine
- clotrimazole
- clozapine
- cobicistat
- coccidioidin skin test
- colchicine
- conivaptan
- copanlisib
- cosibelimab
- COVID-19 mRNA (Moderna) vaccine
- COVID-19 mRNA (Pfizer) vaccine
- crizotinib
- cyclobenzaprine
- cyclosporine
D
- dabrafenib
- danazol
- darifenacin
- darolutamide
- darunavir
- dasatinib
- daunorubicin
- daunorubicin liposomal
- deferasirox
- deferiprone
- degarelix
- delavirdine
- dengue vaccine
- denosumab
- desipramine
- deucravacitinib
- deutetrabenazine
- dexamethasone
- dihydroergotamine
- diltiazem
- dimethyl fumarate
- diroximel fumarate
- disopyramide
- docetaxel
- dofetilide
- dolasetron
- donepezil
- dostarlimab
- doxepin
- doxepin topical
- doxorubicin
- doxorubicin liposomal
- dronedarone
- droperidol
- duloxetine
- durvalumab
- duvelisib
E
- echinacea
- efalizumab
- efavirenz
- efbemalenograstim alfa
- eflapegrastim
- elacestrant
- elafibranor
- elagolix
- eletriptan
- eltrombopag
- empagliflozin
- enasidenib
- encorafenib
- entrectinib
- enzalutamide
- epirubicin
- ergonovine
- ergotamine
- eribulin
- erythromycin
- escitalopram
- eslicarbazepine
- etanercept
- etrasimod
- etravirine
- everolimus
- ezogabine
F
- famotidine
- fedratinib
- felbamate
- felodipine
- fenfluramine
- fentanyl
- fexinidazole
- filgrastim
- fingolimod
- flecainide
- fluconazole
- fluoxetine
- fluphenazine
- flutamide
- fluvoxamine
- formoterol
- fosamprenavir
- fosaprepitant
- foscarnet
- fosphenytoin
- fostamatinib
- fostemsavir
G
- galantamine
- ganciclovir
- gatifloxacin
- gemifloxacin
- gepirone
- gilteritinib
- givinostat
- glasdegib
- glycerin
- goldenseal
- golimumab
- goserelin
- granisetron
- grepafloxacin
- griseofulvin
H
- haemophilus b conjugate (hboc) vaccine
- haemophilus b conjugate (prp-omp) vaccine
- haemophilus b conjugate (prp-t) vaccine
- halofantrine
- haloperidol
- halothane
- hepatitis a adult vaccine
- hepatitis a pediatric vaccine
- hepatitis b adult vaccine
- hepatitis b pediatric vaccine
- histoplasmin
- histrelin
- human papillomavirus vaccine
- hydroxychloroquine
- hydroxyzine
I
- ibrutinib
- ibutilide
- idarubicin
- idelalisib
- iloperidone
- imatinib
- imipramine
- indacaterol
- indinavir
- infliximab
- influenza virus vaccine, h1n1, inactivated
- influenza virus vaccine, h1n1, live
- influenza virus vaccine, h5n1
- influenza virus vaccine, inactivated
- influenza virus vaccine, live
- inotuzumab ozogamicin
- ipilimumab
- iptacopan
- irinotecan
- irinotecan liposomal
- isavuconazonium
- isoetharine
- isoniazid
- isoproterenol
- itraconazole
- ivabradine
- ivacaftor
- ivosidenib
J
K
L
- lactitol
- lactobacillus acidophilus
- lactobacillus reuteri
- lactobacillus rhamnosus
- lactobacillus rhamnosus gg
- lactulose
- lapatinib
- larotrectinib
- lasmiditan
- lazertinib
- lefamulin
- leflunomide
- lemborexant
- lenacapavir
- leniolisib
- lenvatinib
- letermovir
- leuprolide
- levalbuterol
- levobupivacaine
- levofloxacin
- levoketoconazole
- levomethadyl acetate
- lidocaine
- lisdexamfetamine
- lithium
- lofexidine
- lomefloxacin
- lomitapide
- lonafarnib
- lonapegsomatropin
- loncastuximab tesirine
- loperamide
- lorlatinib
- lovastatin
- lurasidone
- lusutrombopag
- lyme disease vaccine
M
- macimorelin
- magnesium citrate
- magnesium hydroxide
- maprotiline
- maraviroc
- maribavir
- mavacamten
- mavorixafor
- measles virus vaccine
- mefloquine
- melatonin
- meningococcal conjugate vaccine
- meningococcal group acwy conjugate-group b vaccine (cvx 316)
- meningococcal group B vaccine
- meningococcal polysaccharide vaccine
- mephobarbital
- mesoridazine
- metaproterenol
- methadone
- methotrexate
- methotrimeprazine
- methylergonovine
- methysergide maleate
- metreleptin
- metronidazole
- mibefradil
- miconazole
- midazolam
- midostaurin
- mifepristone
- mineral oil
- mirtazapine
- mitapivat
- mitotane
- mixed respiratory vaccine
- mobocertinib
- modafinil
- monomethyl fumarate
- morphine
- moxifloxacin
- mumps skin test antigen
- mumps virus vaccine
N
- nadofaragene firadenovec
- nafcillin
- naloxegol
- natalizumab
- nefazodone
- nelfinavir
- neratinib
- nevirapine
- nifedipine
- nilotinib
- nilutamide
- niraparib
- nirogacestat
- nitisinone
- nivolumab
- norfloxacin
- nortriptyline
O
- ocrelizumab
- ofloxacin
- olanzapine
- olaparib
- oliceridine
- olodaterol
- olutasidenib
- omacetaxine
- omaveloxolone
- ondansetron
- oritavancin
- osilodrostat
- oteseconazole
- oxaliplatin
- oxcarbazepine
- oxycodone
- oxytocin
- ozanimod
P
- pacritinib
- palbociclib
- palifermin
- paliperidone
- palonosetron
- panobinostat
- papaverine
- pasireotide
- pazopanib
- pegfilgrastim
- pembrolizumab
- pentamidine
- pentobarbital
- perflutren
- perphenazine
- pertussis, acellular
- pexidartinib
- phenobarbital
- phenolphthalein
- phenylbutazone
- phenytoin
- pimavanserin
- pimozide
- pirbuterol
- pirfenidone
- pirtobrutinib
- pitolisant
- plague vaccine
- pneumococcal 13-valent vaccine
- pneumococcal 15-valent conjugate vaccine
- pneumococcal 20-valent conjugate vaccine
- pneumococcal 21-valent conjugate vaccine
- pneumococcal 23-polyvalent vaccine
- pneumococcal 7-valent vaccine
- poliovirus vaccine, inactivated
- poliovirus vaccine, live, trivalent
- polyethylene glycol 3350
- polyethylene glycol 3350 with electrolytes
- ponesimod
- posaconazole
- pralsetinib
- primaquine
- primidone
- probucol
- procainamide
- prochlorperazine
- promazine
- promethazine
- propafenone
- propofol
- propoxyphene
- propranolol
- protriptyline
Q
R
- rabies vaccine, human diploid cell
- rabies vaccine, purified chick embryo cell
- radium 223 dichloride
- ranolazine
- rasagiline
- red yeast rice
- relugolix
- remdesivir
- repotrectinib
- retifanlimab
- revumenib
- ribociclib
- rifabutin
- rifampin
- rifapentine
- rilonacept
- rilpivirine
- riluzole
- rimegepant
- ripretinib
- risperidone
- ritlecitinib
- ritodrine
- ritonavir
- rivastigmine
- roflumilast
- romidepsin
- ropeginterferon alfa-2b
- ropinirole
- rosuvastatin
- rotavirus vaccine
- rsv vaccine pref3, recombinant
- rsv vaccine, mrna
- rsv vaccine, pref a-pref b, recombinant
- rubella virus vaccine
- rucaparib
- rufinamide
S
- saccharomyces boulardii lyo
- salmeterol
- samarium sm 153 lexidronam
- saquinavir
- sargramostim
- sars-cov-2 (covid-19) ad26 vaccine, recombinant
- sars-cov-2 (covid-19) chadox1 vaccine, recombinant
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 308)
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 309)
- sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 310)
- sars-cov-2 (covid-19) nvx-cov2373 vaccine, recombinant
- sars-cov-2 (covid-19) rs-nanoparticle vaccine, recombinant
- sars-cov-2 mrna (tozinameran 5y-11y) vaccine
- sars-cov-2 mrna (tozinameran 6m-4y) vaccine
- sars-cov-2 mrna (tozinameran-tris-sucrose) vaccine
- sars-cov-2 mrna (tozinameran) vaccine
- sars-cov-2 mrna-1273 (6m-5y) vaccine
- sars-cov-2 mrna-1273 (6y-11y) vaccine
- sars-cov-2 mrna-1273 (booster only) vaccine
- sars-cov-2 nvx-cov2373 vaccine, recomb (cvx 313)
- sars-cov-2 pres dtm (booster only) vaccine, recombinant
- secobarbital
- seladelpar
- selexipag
- selpercatinib
- senna
- sertraline
- sevoflurane
- sildenafil
- simvastatin
- siponimod
- sipuleucel-T
- sirolimus
- skin test antigens, multiple
- smallpox and mpox vaccine
- smallpox vaccine
- sodium phosphate p32
- solifenacin
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sorafenib
- sotalol
- sotorasib
- sparfloxacin
- st. john's wort
- staphage lysate (spl)
- stiripentol
- streptococcus salivarius
- strontium-89 chloride
- sufentanil
- sulfamethoxazole
- sulfasalazine
- sulfinpyrazone
- sunitinib
- suvorexant
- suzetrigine
T
- tacrine
- tacrolimus
- talazoparib
- talimogene laherparepvec
- tamoxifen
- tasimelteon
- tazemetostat
- tbo-filgrastim
- tebentafusp
- tecovirimat
- tedizolid
- telaprevir
- telavancin
- telithromycin
- telotristat
- temsirolimus
- tepotinib
- terbutaline
- terfenadine
- teriflunomide
- tetanus toxoid
- tetrabenazine
- thalidomide
- theophylline
- thioridazine
- ticagrelor
- tick-borne encephalitis (inactivated) pediatric vaccine
- tick-borne encephalitis (inactivated) vaccine
- tipranavir
- tislelizumab
- tizanidine
- tofacitinib
- tolvaptan
- topotecan
- toremifene
- toripalimab
- tovorafenib
- tramadol
- trazodone
- tremelimumab
- treosulfan
- triazolam
- trichophyton skin test
- triclabendazole
- trifluoperazine
- triflupromazine
- trimeprazine
- trimipramine
- triptorelin
- trofinetide
- troglitazone
- troleandomycin
- tuberculin purified protein derivative
- tucatinib
- typhoid vaccine, inactivated
- typhoid vaccine, live
U
V
- vadadustat
- valbenazine
- valganciclovir
- vandetanib
- vardenafil
- varicella virus vaccine
- vasopressin
- vemurafenib
- venetoclax
- venlafaxine
- verapamil
- vibegron
- viloxazine
- vinblastine
- vincristine
- vincristine liposome
- vinorelbine
- voclosporin
- vonoprazan
- vorasidenib
- voriconazole
- voxelotor
W
Y
Z
Tagrisso alcohol/food interactions
There is 1 alcohol/food interaction with Tagrisso (osimertinib).
Tagrisso disease interactions
There are 6 disease interactions with Tagrisso (osimertinib) which include:
- cardiomyopathy
- dermatologic toxicities
- ocular disorders
- pulmonary toxicity
- QT prolongation
- renal/liver impairment
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More about Tagrisso (osimertinib)
- Tagrisso consumer information
- Check interactions
- Compare alternatives
- Pricing & coupons
- Reviews (38)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: EGFR inhibitors
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
