Drug Interactions between methotrexate and Skyrizi
This report displays the potential drug interactions for the following 2 drugs:
- methotrexate
- Skyrizi (risankizumab)
Interactions between your drugs
No interactions were found between methotrexate and Skyrizi. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
methotrexate
A total of 696 drugs are known to interact with methotrexate.
- Methotrexate is in the following drug classes: antimetabolites, antipsoriatics, antirheumatics, other immunosuppressants.
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Methotrexate is used to treat the following conditions:
- Acute Lymphoblastic Leukemia
- Acute Lymphocytic Leukemia
- Acute Nonlymphocytic Leukemia (off-label)
- Bladder Cancer (off-label)
- Brain Tumor (off-label)
- Breast Cancer
- Bullous Pemphigoid (off-label)
- Cervical Cancer (off-label)
- Choriocarcinoma
- Cogan's Syndrome (off-label)
- Colorectal Cancer (off-label)
- Dermatomyositis
- Ectopic Pregnancy (off-label)
- Eczema (off-label)
- Esophageal Carcinoma (off-label)
- Gastric Cancer (off-label)
- Graft-versus-host disease
- Head and Neck Cancer
- Hodgkin's Lymphoma (off-label)
- Lymphoma
- Mantle Cell Lymphoma (off-label)
- Meningeal Leukemia
- Mycosis Fungoides
- Neoplastic Diseases
- Non Small Cell Lung Cancer
- Non-Hodgkin's Lymphoma
- Osteosarcoma
- Ovarian Cancer (off-label)
- Pancreatic Cancer (off-label)
- Pemphigoid (off-label)
- Pemphigus (off-label)
- Pityriasis rubra pilaris (off-label)
- Polyarticular Juvenile Idiopathic Arthritis
- Psoriasis
- Psoriatic Arthritis
- Rheumatoid Arthritis
- Scleroderma (off-label)
- Small Cell Lung Cancer
- Soft Tissue Sarcoma (off-label)
- Solid Tumors
- Systemic Sclerosis
- Trophoblastic Disease
- Uveitis (off-label)
Skyrizi
A total of 164 drugs are known to interact with Skyrizi.
- Skyrizi is in the drug class interleukin inhibitors.
- Skyrizi is used to treat the following conditions:
Drug and food interactions
methotrexate food
Applies to: methotrexate
Caffeine may reduce the effectiveness of methotrexate in the treatment of arthritis. If you are receiving methotrexate for arthritis, you may want to limit your intake of caffeine-containing foods and medications. Check with your doctor or pharmacist if you have concerns or are uncertain what products may contain caffeine.
methotrexate food
Applies to: methotrexate
Methotrexate may cause liver problems, and using it with other medications that can also affect the liver such as ethanol may increase that risk. You should avoid or limit the use of alcohol while being treated with these medications. Call your doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes, as these may be signs and symptoms of liver damage. Talk to your doctor or pharmacist if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
methotrexate food
Applies to: methotrexate
Caffeine may reduce the effectiveness of methotrexate in the treatment of arthritis. If you are receiving methotrexate for arthritis, you may want to limit your intake of caffeine-containing foods and products. Contact your doctor if your symptoms worsen or your condition changes during treatment with these medications. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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