Vyvanse Drug Interactions
Currently displaying a list of 394 drugs known to interact with Vyvanse (lisdexamfetamine).
- 100 major drug interactions
- 285 moderate drug interactions
- 9 minor drug interactions
Medications known to interact with Vyvanse
Note: Showing generic names only.
A
- abarelix
- abiraterone
- adagrasib
- adenosine
- albuterol
- alfentanil
- alfuzosin
- almotriptan
- aluminum carbonate
- aluminum hydroxide
- amifampridine
- aminophylline
- amiodarone
- amisulpride
- amitriptyline
- ammonium chloride
- amoxapine
- amphetamine
- anagrelide
- apalutamide
- apomorphine
- apraclonidine ophthalmic
- arformoterol
- aripiprazole
- armodafinil
- arsenic trioxide
- asciminib
- ascorbic acid
- asenapine
- astemizole
- atomoxetine
- azithromycin
B
- bedaquiline
- benzgalantamine
- benzphetamine
- bepridil
- berotralstat
- bicalutamide
- bisacodyl
- bitolterol
- bosutinib
- buprenorphine
- bupropion
- buspirone
C
- cabozantinib
- caffeine
- calcium carbonate
- casanthranol
- cascara sagrada
- castor oil
- celecoxib
- ceritinib
- chloroquine
- chlorpromazine
- cilostazol
- cimetidine
- cinacalcet
- ciprofloxacin
- cisapride
- citalopram
- clarithromycin
- clobazam
- clofazimine
- clomipramine
- clozapine
- cobicistat
- cocaine nasal
- cocaine topical
- crizotinib
D
- dacomitinib
- darifenacin
- darolutamide
- dasatinib
- daunorubicin
- daunorubicin liposomal
- degarelix
- delavirdine
- deserpidine
- desipramine
- desvenlafaxine
- deutetrabenazine
- dexfenfluramine
- dexmethylphenidate
- dextroamphetamine
- dextromethorphan
- didanosine
- diethylpropion
- dihydroxyaluminum sodium carbonate
- disopyramide
- dobutamine
- dofetilide
- dolasetron
- donepezil
- dopamine
- doxapram
- doxepin
- doxepin topical
- doxorubicin
- doxorubicin liposomal
- dronedarone
- droperidol
- droxidopa
- duloxetine
E
- efavirenz
- eletriptan
- eliglustat
- encorafenib
- entrectinib
- enzalutamide
- ephedrine
- epinephrine
- epirubicin
- eribulin
- erythromycin
- escitalopram
- esketamine
- ethanol
- ethosuximide
- etrasimod
- evening primrose
- ezogabine
F
- famotidine
- fedratinib
- fenfluramine
- fentanyl
- fesoterodine
- fexinidazole
- fingolimod
- flecainide
- fluconazole
- fluoxetine
- fluphenazine
- flutamide
- fluvoxamine
- formoterol
- foscarnet
- fostemsavir
- frovatriptan
- furazolidone
G
- galantamine
- gatifloxacin
- gemifloxacin
- gepirone
- gilteritinib
- ginkgo
- givinostat
- givosiran
- glasdegib
- glutamic acid
- glycerin
- glycerol phenylbutyrate
- goserelin
- granisetron
- grepafloxacin
- guanadrel
- guanethidine
- guanfacine
H
I
- ibutilide
- idarubicin
- iloperidone
- imatinib
- imipramine
- indacaterol
- inotuzumab ozogamicin
- iobenguane I 123
- iobenguane I 131
- ioflupane I 123
- iohexol
- iomeprol
- iopamidol
- isocarboxazid
- isoetharine
- isoproterenol
- ivabradine
- ivosidenib
K
L
- lactitol
- lactulose
- lapatinib
- lefamulin
- lenvatinib
- leuprolide
- levalbuterol
- levofloxacin
- levoketoconazole
- levomethadyl acetate
- levomilnacipran
- levothyroxine
- lindane topical
- linezolid
- liothyronine
- lithium
- lofexidine
- lomefloxacin
- loperamide
- lorcaserin
M
- ma huang
- macimorelin
- magaldrate
- magnesium carbonate
- magnesium citrate
- magnesium hydroxide
- magnesium oxide
- maprotiline
- mavorixafor
- mazindol
- mefloquine
- meperidine
- mephentermine
- mesoridazine
- metaproterenol
- metaraminol
- methadone
- methamphetamine
- methdilazine
- methenamine
- methotrimeprazine
- methoxamine
- methylene blue
- methylphenidate
- metrizamide
- metronidazole
- mibefradil
- midodrine
- midostaurin
- mifepristone
- milnacipran
- mineral oil
- mirabegron
- mirtazapine
- mobocertinib
- modafinil
- moxifloxacin
N
O
- ofloxacin
- olanzapine
- oliceridine
- olodaterol
- ondansetron
- oritavancin
- osilodrostat
- osimertinib
- oxaliplatin
- oxamniquine
- oxytocin
- ozanimod
P
- pacritinib
- paliperidone
- palonosetron
- panobinostat
- papaverine
- paroxetine
- pasireotide
- pazopanib
- pentamidine
- pentazocine
- perflutren
- perphenazine
- phendimetrazine
- phenelzine
- phenobarbital
- phenolphthalein
- phentermine
- phenylephrine
- phenylpropanolamine
- phenytoin
- pimavanserin
- pimozide
- pirbuterol
- pitolisant
- polyethylene glycol 3350
- polyethylene glycol 3350 with electrolytes
- ponesimod
- posaconazole
- potassium acid phosphate
- potassium citrate
- pralsetinib
- primaquine
- probucol
- procainamide
- procarbazine
- prochlorperazine
- promazine
- promethazine
- propafenone
- propiomazine
- propofol
- propoxyphene
- protriptyline
- prucalopride
- pseudoephedrine
Q
R
- racepinephrine
- ranolazine
- rasagiline
- rauwolfia serpentina
- relugolix
- remifentanil
- reserpine
- revumenib
- ribociclib
- rilpivirine
- risperidone
- ritodrine
- ritonavir
- rivastigmine
- rizatriptan
- rolapitant
- romidepsin
- rucaparib
S
- safinamide
- salmeterol
- saquinavir
- selegiline
- selpercatinib
- senna
- sertraline
- sevoflurane
- sibutramine
- siponimod
- sodium acetate
- sodium bicarbonate
- sodium citrate
- sodium lactate
- solifenacin
- solriamfetol
- sorafenib
- sotalol
- sparfloxacin
- st. john's wort
- stiripentol
- sufentanil
- sulfamethoxazole
- sumatriptan
- sunitinib
T
- tacrine
- tacrolimus
- tamoxifen
- tapentadol
- tebentafusp
- telavancin
- telithromycin
- terbinafine
- terbutaline
- terfenadine
- tetrabenazine
- thalidomide
- theophylline
- thiethylperazine
- thioridazine
- thyroid desiccated
- tirzepatide
- tizanidine
- toremifene
- tramadol
- tranylcypromine
- trazodone
- triclabendazole
- trifluoperazine
- triflupromazine
- trimeprazine
- trimipramine
- triptorelin
- tromethamine
- tryptophan
V
- valbenazine
- vandetanib
- vardenafil
- vasopressin
- vemurafenib
- venlafaxine
- vilazodone
- viloxazine
- voclosporin
- voriconazole
- vorinostat
- vortioxetine
Z
Vyvanse alcohol/food interactions
There are 3 alcohol/food interactions with Vyvanse (lisdexamfetamine).
Vyvanse disease interactions
There are 10 disease interactions with Vyvanse (lisdexamfetamine) which include:
- cardiovascular
- glaucoma
- agitation
- cardiac disease
- hypertension
- psychiatric disorders
- substance abuse
- tics
- seizure disorders
- renal dysfunction
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- Drug class: CNS stimulants
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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