Orkambi (ivacaftor / lumacaftor) Drug Interactions
A total of 536 drugs (2567 brand and generic names) are known to interact with Orkambi (ivacaftor / lumacaftor).
- 210 major drug interactions (1198 brand and generic names)
- 320 moderate drug interactions (1357 brand and generic names)
- 6 minor drug interactions (12 brand and generic names)
Check for interactions with Orkambi (ivacaftor / lumacaftor)
Common medications checked in combination with Orkambi (ivacaftor / lumacaftor)
- albuterol
- amlodipine
- amoxicillin
- azithromycin
- ciprofloxacin
- Creon (pancrelipase)
- lansoprazole
- Lexapro (escitalopram)
- meropenem
- prednisone
- ProAir HFA (albuterol)
- Pulmozyme (dornase alfa)
- Singulair (montelukast)
- tobramycin
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- vitamin e
- Xifaxan (rifaximin)
- Zyrtec (cetirizine)
Orkambi (ivacaftor / lumacaftor) alcohol/food Interactions
There is 1 alcohol/food interaction with Orkambi (ivacaftor / lumacaftor)
See also...
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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