Orkambi (ivacaftor / lumacaftor) Drug Interactions
A total of 570 drugs (2651 brand and generic names) are known to interact with Orkambi (ivacaftor / lumacaftor).
- 231 major drug interactions (1247 brand and generic names)
- 333 moderate drug interactions (1392 brand and generic names)
- 6 minor drug interactions (12 brand and generic names)
Check for interactions with Orkambi (ivacaftor / lumacaftor)
Common medications checked in combination with Orkambi (ivacaftor / lumacaftor)
- albuterol
- amoxicillin
- azithromycin
- Benadryl (diphenhydramine)
- ciprofloxacin
- Control (phenylpropanolamine)
- Creon (pancrelipase)
- Hyper-Sal (sodium chloride)
- ibuprofen
- Kalydeco (ivacaftor)
- lansoprazole
- meropenem
- Mirena (levonorgestrel)
- oxycodone
- Peri-DS (casanthranol / docusate)
- polyethylene glycol 3350
- prednisone
- ProAir HFA (albuterol)
- Pulmozyme (dornase alfa)
- Symbicort (budesonide / formoterol)
- tobramycin
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- voriconazole
- Zyrtec (cetirizine)
Orkambi (ivacaftor / lumacaftor) alcohol/food Interactions
There is 1 alcohol/food interaction with Orkambi (ivacaftor / lumacaftor)
Orkambi (ivacaftor / lumacaftor) disease Interactions
There are 3 disease interactions with Orkambi (ivacaftor / lumacaftor) which include:
See Also
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No information available. |
Do not stop taking any medications without consulting your healthcare provider.
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