Orkambi Interactions
There are 574 drugs known to interact with Orkambi (ivacaftor/lumacaftor), along with 6 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 256 are major, 304 are moderate, and 14 are minor.
- View all 574 medications that may interact with Orkambi
- View Orkambi alcohol/food interactions (2)
- View Orkambi disease interactions (6)
Most frequently checked interactions
View interaction reports for Orkambi (ivacaftor / lumacaftor) and the medicines listed below.
- albuterol
- amitriptyline
- amoxicillin
- azithromycin
- Cayston (aztreonam)
- ciprofloxacin
- clofazimine
- Corifact (factor XIII)
- Creon (pancrelipase)
- Dulera (formoterol / mometasone)
- Humalog (insulin lispro)
- Hyper-Sal (sodium chloride)
- ibuprofen
- Kalydeco (ivacaftor)
- lansoprazole
- meropenem
- MiraLAX (polyethylene glycol 3350)
- Nucala (mepolizumab)
- omeprazole
- oxycodone
- prednisone
- ProAir HFA (albuterol)
- Pulmozyme (dornase alfa)
- Qvar RediHaler (beclomethasone)
- Remeron (mirtazapine)
- Symbicort (budesonide / formoterol)
- tobramycin
- Trikafta (elexacaftor / ivacaftor / tezacaftor)
- Vitamin D3 (cholecalciferol)
- Zyrtec (cetirizine)
Orkambi alcohol/food interactions
There are 2 alcohol/food interactions with Orkambi (ivacaftor / lumacaftor).
Orkambi disease interactions
There are 6 disease interactions with Orkambi (ivacaftor / lumacaftor) which include:
Report options
More about Orkambi (ivacaftor / lumacaftor)
- Orkambi consumer information
- Compare alternatives
- Pricing & coupons
- Drug images
- Side effects
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: CFTR combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Zithromax
Zithromax (azithromycin) treats infections caused by bacteria, such as respiratory infections, skin ...
Creon
Creon (pancrelipase) contains digestive enzymes and is used to improve food digestion in people who ...
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Zenpep
Zenpep (pancrealipase) is used to replace pancreatic enzymes when the body does not have enough of ...
Vitamin e
Vitamin E is an antioxidant that occurs naturally in some foods and is used to treat or prevent ...
Pancrelipase
Pancrelipase systemic is used for chronic pancreatitis, cystic fibrosis, pancreatic exocrine dysfunction
Mannitol
Mannitol systemic is used for cerebral edema, cystic fibrosis, diagnosis and investigation, oliguria
Amikacin
Amikacin systemic is used for bacteremia, bone infection, cystic fibrosis, febrile neutropenia ...
Tobramycin
Tobramycin systemic is used for bacteremia, bacterial infection, bone infection, burns, external ...
Gentamicin
Gentamicin systemic is used for bacteremia, bacterial endocarditis prevention, bacterial infection ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
