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Orkambi (ivacaftor / lumacaftor) Drug Interactions

A total of 456 drugs are known to interact with Orkambi (ivacaftor / lumacaftor).

  • 186 major drug interactions
  • 263 moderate drug interactions
  • 7 minor drug interactions

Show all medications in the database that may interact with Orkambi (ivacaftor / lumacaftor).

Check for interactions

Type in a drug name to check for interactions with Orkambi (ivacaftor / lumacaftor).

Most frequently checked interactions

View interaction reports for Orkambi (ivacaftor / lumacaftor) and the medicines listed below.

Orkambi (ivacaftor / lumacaftor) alcohol/food interactions

There are 2 alcohol/food interactions with Orkambi (ivacaftor / lumacaftor)

Orkambi (ivacaftor / lumacaftor) disease interactions

There are 6 disease interactions with Orkambi (ivacaftor / lumacaftor) which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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