Tofranil-PM Interactions
There are 739 drugs known to interact with Tofranil-PM (imipramine), along with 20 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 143 are major, 569 are moderate, and 27 are minor.
- View all 739 medications that may interact with Tofranil-PM
- View Tofranil-PM alcohol/food interactions (2)
- View Tofranil-PM disease interactions (20)
Most frequently checked interactions
View interaction reports for Tofranil-PM (imipramine) and the medicines listed below.
- acetaminophen / caffeine / isometheptene mucate
- acetaminophen / caffeine / isometheptene mucate
- Adasuve (loxapine)
- Adasuve (loxapine)
- Advate (antihemophilic factor)
- Advate (antihemophilic factor)
- Benadryl (diphenhydramine)
- Benadryl (diphenhydramine)
- gabapentin
- gabapentin
- lisinopril
- lisinopril
- Lyrica (pregabalin)
- Lyrica (pregabalin)
- metformin
- metformin
- Norco (acetaminophen / hydrocodone)
- Norco (acetaminophen / hydrocodone)
- Phenergan (promethazine)
- Phenergan (promethazine)
- Prevacid (lansoprazole)
- Prevacid (lansoprazole)
- Prilosec (omeprazole)
- Prilosec (omeprazole)
- tramadol
- tramadol
- trazodone
- trazodone
- Zofran ODT (ondansetron)
- Zofran ODT (ondansetron)
Tofranil-PM alcohol/food interactions
There are 2 alcohol/food interactions with Tofranil-PM (imipramine).
Tofranil-PM disease interactions
There are 20 disease interactions with Tofranil-PM (imipramine) which include:
- anticholinergic effects
- cardiovascular disease
- pheochromocytoma
- acute myocardial infarction recovery
- cardiovascular disease
- seizure disorders
- bone marrow suppression
- diabetes
- renal/liver disease
- schizophrenia/bipolar disorder
- tardive dyskinesia
- acute alcohol intoxication
- bipolar disorder screening
- glaucoma
- hyper/hypoglycemia
- liver/renal disease
- neutropenia
- schizophrenia
- thyroid disorders
- urinary retention
Report options
More about Tofranil-PM (imipramine)
- Tofranil-PM consumer information
- Compare alternatives
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: tricyclic antidepressants
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
