Hydrocodone/pseudoephedrine Interactions
There are 727 drugs known to interact with hydrocodone/pseudoephedrine, along with 22 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 220 are major, 501 are moderate, and 6 are minor.
- View all 727 medications that may interact with hydrocodone/pseudoephedrine
- View hydrocodone/pseudoephedrine alcohol/food interactions (1)
- View hydrocodone/pseudoephedrine disease interactions (22)
Most frequently checked interactions
View interaction reports for hydrocodone / pseudoephedrine and the medicines listed below.
- Aciphex (rabeprazole)
- Actiq (fentanyl)
- Adderall (amphetamine / dextroamphetamine)
- Afrin (oxymetazoline nasal)
- Aloxi (palonosetron)
- Ambien (zolpidem)
- Aminomine (tryptophan)
- Anafranil (clomipramine)
- Asendin (amoxapine)
- Asmanex HFA (mometasone)
- Astelin (azelastine nasal)
- Atrovent HFA (ipratropium)
- Augmentin (amoxicillin / clavulanate)
- Azo Urinary Pain Relief (phenazopyridine)
- Azo-Standard (phenazopyridine)
- Bayer Advanced Aspirin (aspirin)
- Belladonna Tincture (belladonna)
- Benadryl (diphenhydramine)
- Bentyl (dicyclomine)
- Breo Ellipta (fluticasone / vilanterol)
- Bromax (brompheniramine)
- Bupap (acetaminophen / butalbital)
- Lunesta (eszopiclone)
- Lyrica (pregabalin)
- Prozac (fluoxetine)
- Sudafed Congestion (pseudoephedrine)
- Synthroid (levothyroxine)
- Tylenol with Codeine #3 (acetaminophen / codeine)
- Xopenex HFA (levalbuterol)
- Zoloft (sertraline)
Hydrocodone/pseudoephedrine alcohol/food interactions
There is 1 alcohol/food interaction with hydrocodone / pseudoephedrine.
Hydrocodone/pseudoephedrine disease interactions
There are 22 disease interactions with hydrocodone / pseudoephedrine which include:
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- cardiovascular disease
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
- GI narrowing
- PKU
- BPH
- diabetes
- glaucoma
Report options
More about hydrocodone / pseudoephedrine
- hydrocodone/pseudoephedrine consumer information
- Compare alternatives
- Reviews (6)
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
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Robitussin Nighttime Cough DM
Robitussin Nighttime Cough DM is used for cough, cough and nasal congestion
Vicks Nyquil Cough
Vicks Nyquil Cough is used for cough, cough and nasal congestion
Dextromethorphan/guaifenesin/phenylephrine
Dextromethorphan/guaifenesin/phenylephrine systemic is used for cough and nasal congestion
Brompheniramine/dextromethorphan/pseudoephedrine
Brompheniramine/dextromethorphan/pseudoephedrine systemic is used for cough and nasal congestion
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.