Hydrocodone/pseudoephedrine Interactions
There are 728 drugs known to interact with hydrocodone/pseudoephedrine, along with 22 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 221 are major, 501 are moderate, and 6 are minor.
- View all 728 medications that may interact with hydrocodone/pseudoephedrine
- View hydrocodone/pseudoephedrine alcohol/food interactions (1)
- View hydrocodone/pseudoephedrine disease interactions (22)
Most frequently checked interactions
View interaction reports for hydrocodone / pseudoephedrine and the medicines listed below.
- Aciphex (rabeprazole)
- Actiq (fentanyl)
- Adderall (amphetamine / dextroamphetamine)
- Afrin (oxymetazoline nasal)
- Aloxi (palonosetron)
- Ambien (zolpidem)
- Aminomine (tryptophan)
- Anafranil (clomipramine)
- Asendin (amoxapine)
- Asmanex HFA (mometasone)
- Astelin (azelastine nasal)
- Atrovent HFA (ipratropium)
- Augmentin (amoxicillin / clavulanate)
- Azo Urinary Pain Relief (phenazopyridine)
- Azo-Standard (phenazopyridine)
- Bayer Advanced Aspirin (aspirin)
- Belladonna Tincture (belladonna)
- Benadryl (diphenhydramine)
- Bentyl (dicyclomine)
- Breo Ellipta (fluticasone / vilanterol)
- Bromax (brompheniramine)
- Bupap (acetaminophen / butalbital)
- Lunesta (eszopiclone)
- Lyrica (pregabalin)
- Prozac (fluoxetine)
- Sudafed Congestion (pseudoephedrine)
- Synthroid (levothyroxine)
- Tylenol with Codeine #3 (acetaminophen / codeine)
- Xopenex HFA (levalbuterol)
- Zoloft (sertraline)
Hydrocodone/pseudoephedrine alcohol/food interactions
There is 1 alcohol/food interaction with hydrocodone / pseudoephedrine.
Hydrocodone/pseudoephedrine disease interactions
There are 22 disease interactions with hydrocodone / pseudoephedrine which include:
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- cardiovascular disease
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
- GI narrowing
- PKU
- BPH
- diabetes
- glaucoma
Report options
QR code containing a link to this page
More about hydrocodone / pseudoephedrine
- hydrocodone/pseudoephedrine consumer information
- Compare alternatives
- Reviews (6)
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.