Hydrocodone / pseudoephedrine Drug Interactions
A total of 633 drugs are known to interact with hydrocodone / pseudoephedrine.
- 204 major drug interactions
- 424 moderate drug interactions
- 5 minor drug interactions
Check for interactions
Most frequently checked interactions
View interaction reports for hydrocodone / pseudoephedrine and the medicines listed below.
- Aciphex (rabeprazole)
- Actiq (fentanyl)
- Adderall (amphetamine / dextroamphetamine)
- Afrin (oxymetazoline nasal)
- Aloxi (palonosetron)
- Ambien (zolpidem)
- Aminomine (tryptophan)
- Anafranil (clomipramine)
- Asendin (amoxapine)
- Asmanex HFA (mometasone)
- Astelin (azelastine nasal)
- Atrovent HFA (ipratropium)
- Bayer Advanced Aspirin (aspirin)
- Lunesta (eszopiclone)
- Lyrica (pregabalin)
- Prozac (fluoxetine)
- Sudafed Congestion (pseudoephedrine)
- Tylenol with Codeine #3 (acetaminophen / codeine)
- Xopenex HFA (levalbuterol)
- Zoloft (sertraline)
Hydrocodone / pseudoephedrine alcohol/food interactions
There is 1 alcohol/food interaction with hydrocodone / pseudoephedrine
Hydrocodone / pseudoephedrine disease interactions
There are 23 disease interactions with hydrocodone / pseudoephedrine which include:
- impaired GI motility
- infectious diarrhea
- liver disease
- prematurity
- acute alcohol intoxication
- drug dependence
- gastrointestinal obstruction
- hypotension
- intracranial pressure
- respiratory depression
- cardiovascular disease
- adrenal insufficiency
- biliary spasm
- hypothyroidism
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- GI narrowing
- PKU
- BPH
- diabetes
- glaucoma
More about hydrocodone / pseudoephedrine
- Side Effects
- During Pregnancy
- Dosage Information
- 5 Reviews
- Drug class: upper respiratory combinations
- FDA Alerts (1)
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.