Hydrocodone/pseudoephedrine Interactions
There are 729 drugs known to interact with hydrocodone/pseudoephedrine, along with 22 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 220 are major, 503 are moderate, and 6 are minor.
- View all 729 medications that may interact with hydrocodone/pseudoephedrine
- View hydrocodone/pseudoephedrine alcohol/food interactions (1)
- View hydrocodone/pseudoephedrine disease interactions (22)
Most frequently checked interactions
View interaction reports for hydrocodone / pseudoephedrine and the medicines listed below.
- Aciphex (rabeprazole)
- Aciphex (rabeprazole)
- Actiq (fentanyl)
- Actiq (fentanyl)
- Adderall (amphetamine / dextroamphetamine)
- Adderall (amphetamine / dextroamphetamine)
- Afrin (oxymetazoline nasal)
- Afrin (oxymetazoline nasal)
- Aloxi (palonosetron)
- Aloxi (palonosetron)
- Ambien (zolpidem)
- Ambien (zolpidem)
- Aminomine (tryptophan)
- Aminomine (tryptophan)
- Lunesta (eszopiclone)
- Lunesta (eszopiclone)
- Lyrica (pregabalin)
- Lyrica (pregabalin)
- Prozac (fluoxetine)
- Prozac (fluoxetine)
- Sudafed Congestion (pseudoephedrine)
- Sudafed Congestion (pseudoephedrine)
- Synthroid (levothyroxine)
- Synthroid (levothyroxine)
- Tylenol with Codeine #3 (acetaminophen / codeine)
- Tylenol with Codeine #3 (acetaminophen / codeine)
- Xopenex HFA (levalbuterol)
- Xopenex HFA (levalbuterol)
- Zoloft (sertraline)
- Zoloft (sertraline)
Hydrocodone/pseudoephedrine alcohol/food interactions
There is 1 alcohol/food interaction with hydrocodone / pseudoephedrine.
Hydrocodone/pseudoephedrine disease interactions
There are 22 disease interactions with hydrocodone / pseudoephedrine which include:
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- cardiovascular disease
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
- GI narrowing
- PKU
- BPH
- diabetes
- glaucoma
Report options
More about hydrocodone / pseudoephedrine
- hydrocodone/pseudoephedrine consumer information
- Compare alternatives
- Reviews (6)
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Promethazine VC with Codeine
Promethazine VC with Codeine is used for cough and nasal congestion
Mucinex D
Mucinex D (guaifenesin and pseudoephedrine) is used to treat nasal and sinus congestion, and to ...
Dupixent
Dupixent is used to treat eczema, eosinophilic or oral-corticosteroid-dependent asthma, chronic ...
Robitussin Nighttime Cough DM
Robitussin Nighttime Cough DM is used for cough, cough and nasal congestion
Brompheniramine/dextromethorphan/pseudoephedrine
Brompheniramine/dextromethorphan/pseudoephedrine is used for cough and nasal congestion
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.