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Fosphenytoin Drug Interactions

Currently displaying 205 drugs known to have a major interaction with fosphenytoin.

See also: The most common drugs checked in combination with this medicine.

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Type in a drug name to check for interactions with fosphenytoin.

Medications known to interact with fosphenytoin

    • edoxaban (Savaysa)
    • efavirenz / emtricitabine / tenofovir (Atripla)
    • efavirenz / lamivudine / tenofovir (Symfi, Symfi Lo)
    • elbasvir / grazoprevir (Zepatier)
    • eliglustat (Cerdelga)
    • elvitegravir (Vitekta)
    • emtricitabine / lopinavir / ritonavir / tenofovir (AccessPak for HIV PEP Expanded with Kaletra)
    • emtricitabine / nelfinavir / tenofovir (AccessPak for HIV PEP Expanded with Viracept)
    • encorafenib (Braftovi)
    • eravacycline (Xerava)
    • estradiol / levonorgestrel (Climara Pro)
    • estradiol / norethindrone (CombiPatch, Activella, Mimvey, Amabelz, Lopreeza, Mimvey Lo, Ena)
    • estradiol / norgestimate (Prefest, Ortho-Prefest)
    • ethinyl estradiol (Estinyl)
    • ethinyl estradiol / ethynodiol (Kelnor 1/35, Zovia 1/35E, Zovia 1/50E, Demulen 1/35, Demulen, Demulen 1/50, Kelnor 1/50, Lo-Malmorede, Malmorede)
    • ethinyl estradiol / etonogestrel (NuvaRing)
    • ethinyl estradiol / folic acid / levonorgestrel (FaLessa Kit)
    • ethinyl estradiol / levonorgestrel (Aviane, Alesse, Seasonique, Lutera, Seasonale, Levora, Orsythia, Portia, Altavera, Amethyst, Amethia, Vienva, Trivora, Lessina, Sronyx, Aubra, Jolessa, Daysee, Camrese, Introvale, Ashlyna, Larissia, Kurvelo, Alesse-28, Falmina, Levlen, Lillow, Balcoltra, LoSeasonique, Lybrel, Setlakin, Nordette, Triphasil, Chateal, Enpresse, Quasense, Simpesse, Levonest, Afirmelle, Amethia Lo, Chateal EQ, Marlissa, Rivelsa, Ayuna, Fayosim, Jaimiess, Alesse-21, Preven EC, CamreseLo, Myzilra, Quartette, Lo Simpesse, Cerinta, Nordette-21, Elifemme, Nordette-28, Tri-Levlen, Triphasil-21, Triphasil-28, Sylevia, Levlite, Triquilar 21, Triquilar 28, Min-Ovral 21, Min-Ovral 28, Delyla, Iclevia, Aubra EQ)
    • ethinyl estradiol / norelgestromin (Xulane, Ortho Evra)
    • ethinyl estradiol / norethindrone (Lo Loestrin Fe, Junel Fe 1/20, Necon 1/35, Taytulla, Microgestin Fe 1/20, Minastrin 24 Fe, Estrostep Fe, Loestrin 21 1/20, Loestrin Fe 1/20, Blisovi 24 Fe, Loestrin 24 Fe, Loestrin Fe 1.5/30, Nortrel 1/35, Junel Fe 1.5/30, Junel 1.5/30, Blisovi Fe 1/20, Junel Fe 24, Mibelas 24 Fe, Jinteli, Microgestin 1/20, Microgestin 1.5/30, Larin Fe 1/20, Melodetta 24 Fe, Blisovi Fe 1.5/30, Pirmella 1/35, Cyclafem 1/35, femhrt, Junel 1/20, Wymzya Fe, Tarina Fe 1/20, Microgestin Fe 1.5/30, Fyavolv, Alyacen 1/35, Layolis Fe, Ortho-Novum 7/7/7, Ortho-Novum 1/35, Necon 0.5/35, Necon 10/11, Necon 7/7/7, Nortrel 0.5/35, Balziva, Femcon Fe, Tri-Legest Fe, Brevicon, Gildess Fe 1/20, Nortrel 7/7/7, Aranelle, Kaitlib Fe, Tri-Legest, Tilia Fe, Dasetta, Vyfemla, Larin 24 Fe, Jevantique, Hailey 24 Fe, Pirmella 7/7/7, Modicon, Ovcon 35, Norinyl 1+35, Loestrin 21 1.5/30, Ovcon 50, Jenest, Ortho-Novum 10/11, Leena, Zenchent Fe, Zenchent, Nylia 1/35, Aurovela Fe 1.5/30, Tarina 24 Fe, Briellyn, Alyacen 7/7/7, Larin Fe 1.5/30, Gildess 1/20, Microgestin 24 Fe, Larin 1.5/30, Larin 1/20, Generess Fe, Gildess 24 Fe, Hailey Fe 1/20, Wera, Cyclafem 7/7/7, Genora 0.5/35, Nelova 0.5/35, Gildess Fe 1.5/30, Genora 1/35, Norethin 1/35 E, Nelova 10/11, Nelova 1/35, Tri-Norinyl, Ovcon 35 Fe, Nylia 7/7/7, Cyonanz, Aurovela 24 Fe, Aurovela Fe 1/20, Aurovela 1/20, Leribane, Aurovela 1.5/30, Cyclafem 0.5/35, Lo Minastrin Fe, Gildagia, Lomedia 24 Fe, Dasetta 7/7/7, Philith, Dasetta 1/35, Zeosa, Hailey 1.5/30, Hailey Fe 1.5/30, Nexesta Fe, Gildess 1.5/30, Jevantique Lo)
    • ethinyl estradiol / norgestimate (Sprintec, Ortho Tri-Cyclen, Tri-Sprintec, TriNessa, Estarylla, Ortho Tri-Cyclen Lo, Mononessa, Tri-Lo-Sprintec, Ortho Cyclen, Femynor, Mono-Linyah, TriNessa Lo, Tri-Lo-Estarylla, Tri-Estarylla, Tri-Linyah, Tri-Lo-Marzia, VyLibra, Tri-Previfem, Previfem, Tri Femynor, Mili, Tri-Vylibra Lo, Tri-VyLibra, Tri-Lo-Mili, Tri-Mili)
    • ethinyl estradiol / norgestrel (Cryselle, Lo/Ovral, Elinest, Ovral, Low-Ogestrel-28, Ogestrel 0.5/50, Lo/Ovral-28, Ovral-28, Ovral-21)
    • ethinyl estradiol / segesterone (Annovera)
    • etonogestrel (Nexplanon, Implanon)
    • etravirine (Intelence)
    • everolimus (Afinitor, Zortress, Afinitor Disperz)
    • gilteritinib (Xospata)
    • glasdegib (Daurismo)
    • guaifenesin / hydrocodone (Hydrocod-GF, Vitussin Expectorant, Narcof, Condasin, Obredon, Vicodin Tuss, Monte-G HC, Flowtuss, CodiCLEAR DH, Maxi-Tuss HCG, EndaCof-Tab, Ztuss ZT, Tusso-HC, Execlear, Hycotuss Expectorant, Pneumotussin HC, Propatuss Expectorant, Kwelcof, Vi-Q-Tuss, Co-Tussin, Codotuss, Fentuss Expectorant, Co-Tuss V Expectorant, Vicoclear, Endacof XP, Hycosin Expectorant, Vicotuss, G-Tuss, Hycoclar Tuss, Cotuss V, Hydrotuss, Gua HC, Hycoclear, Medcodin, Vortex, Pneumotussin 2.5, Entuss, Pneumotussin, Tusso-DF, Execof, Pancof XP, Touro HC, Xpect-HC, Atuss HX, Extendryl HC, Hydro-Tussin HG, Canges-XP, Z-Cof HCX, Tussicle, A-Cof DH, Relasin-HCX)
    • guaifenesin / hydrocodone / pheniramine / phenylephrine / phenylpropanolamine (S-T Forte)
    • guaifenesin / hydrocodone / pheniramine / phenylpropanolamine / pyrilamine
    • guaifenesin / hydrocodone / phenylephrine (Mintuss G, Atuss G, Ambi 5/15/100, Tussafed-HC, Levall 5.0, Hydro GP, De-Chlor G, Dynatuss HC, Tussafed-HCG, Uni-Lev 5.0, Crantex HC, Duratuss HD, Simuc-HD, Gentex HC, Donatussin DC, Guiaplex HC, Exetuss-HC, Qual-Tussin DC, Nariz HC, MonteFlu HC, Nazarin HC, HydroFed)
    • guaifenesin / hydrocodone / pseudoephedrine (Hycofenix, Entuss-D JR, Decotuss-HD, Vanex Expectorant, Tussadur-HD, Tussend Expectorant, Detussin Expectorant, Tussgen Expectorant, SRC Expectorant, Nalex Expectorant, Deconamine CX, Poly-Tussin XP, Entuss-D, Hydrotussin HD, KG-Tuss HD, Medtuss HD, Spantuss HD, Vanacon, Su-Tuss HD Elixir, Tussafin Liquid, Hytussin Expectorant, Drituss HD, Hydro-Tuss XP, Dynex HD, Entex HC, Pseudatex HC)
    • guanfacine (Intuniv, Tenex)

    Fosphenytoin alcohol/food interactions

    There is 1 alcohol/food interaction with fosphenytoin

    Fosphenytoin disease interactions

    There are 12 disease interactions with fosphenytoin which include:

    Drug Interaction Classification

    These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
    Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
    Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
    Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
    Unknown No interaction information available.

    Further information

    Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.