Climara Pro Interactions
There are 453 drugs known to interact with Climara Pro (estradiol/levonorgestrel), along with 23 disease interactions, and 9 alcohol/food interactions. Of the total drug interactions, 73 are major, 353 are moderate, and 27 are minor.
- View all 453 medications that may interact with Climara Pro
- View Climara Pro alcohol/food interactions (9)
- View Climara Pro disease interactions (23)
Most frequently checked interactions
View interaction reports for Climara Pro (estradiol / levonorgestrel) and the medicines listed below.
- atorvastatin
- atorvastatin
- clonazepam
- clonazepam
- cyclobenzaprine
- cyclobenzaprine
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- gabapentin
- gabapentin
- hydrochlorothiazide
- hydrochlorothiazide
- levothyroxine
- levothyroxine
- metformin
- metformin
- omeprazole
- omeprazole
- pantoprazole
- pantoprazole
- prednisone
- prednisone
- Synthroid (levothyroxine)
- Synthroid (levothyroxine)
- trazodone
- trazodone
- Vitamin D3 (cholecalciferol)
- Vitamin D3 (cholecalciferol)
- vitamin e
- vitamin e
Climara Pro alcohol/food interactions
There are 9 alcohol/food interactions with Climara Pro (estradiol / levonorgestrel).
Climara Pro disease interactions
There are 23 disease interactions with Climara Pro (estradiol / levonorgestrel) which include:
- abnormal genital bleeding
- abnormal vaginal bleeding
- carcinomas (estrogenic)
- hypercalcemia in breast cancer
- hypertension
- thromboembolism/cardiovascular
- hepatic neoplasms
- breast malignancy
- liver disease
- angioedema
- gallbladder disease
- hypercalcemia
- hyperlipidemia
- liver disease
- melasma
- depression
- fluid retention
- glucose intolerance
- retinal thrombosis
- thyroid function tests
- cardiovascular disease
- hyperlipidemia
- weight gain
Report options
More about Climara Pro (estradiol / levonorgestrel)
- Climara Pro consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (48)
- Side effects
- Dosage information
- During pregnancy
- Drug class: sex hormone combinations
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.